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  • Perceptions and experiences of early-adopting registered dietitians in integrating nutrigenomics into practice 

    Abrahams M, Frewer LJ, Bryant LJ and Stewart-Knox B (2017) Perceptions and experiences of early-adopting registered dietitians in integrating nutrigenomics into practice. British Food Journal. Accepted for publication, Oct 2017.
    Purpose - This research explores the perceptions and experiences of early adopters of the technology. Design/Method/Approach - Registered Dietitians (RD´s) (N=14) were recruited from the UK, Canada, South-Africa, ...
  • A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota 

    Watson H, Mitra S, Croden FC, et al (2017) A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota. Gut. Published Online before print.
    Abstract Objective Omega-3 polyunsaturated fatty acids (PUFAs) have anticolorectal cancer (CRC) activity. The intestinal microbiota has been implicated in colorectal carcinogenesis. Dietary omega-3 PUFAs alter the mouse ...
  • A qualitative study of patient involvement in medicines management after hospital discharge: an under-recognised source of systems resilience 

    Fylan B, Armitage G, Naylor D et al (2017) A qualitative study of patient involvement in medicines management after hospital discharge: an under-recognised source of systems resilience. BMJ Quality & Safety. Accepted for Publication.
    Introduction: There are risks to the safety of medicines management when patient care is transferred between healthcare organisations, for example when a patient is discharged from hospital. Using the theoretical concept ...
  • Tracking cell proliferation using a nanotechnology based approach 

    Altea-Manzano P, Unciti-Broceta JD, Cano-Cortes V, Ruiz-Blas MP, Valero-Grinan Teresa M, Diaz-Mochon JJ and Sanchez-Martin R (2017) Tracking cell proliferation using a nanotechnology-based approach. Nanomedicine. 12(13): 1591-1605.
    To develop an efficient nanotechnology fluorescence-based method to track cell proliferation to avoid the limitations of current cell-labeling dyes. Material & methods: Synthesis, PEGylation, bifunctionalization and labeling ...
  • Mitochondrial Biogenesis: Pharmacological Approaches 

    Valero-Grinan T (2014) Editorial (Thematic Issue: Mitochondrial Biogenesis: Pharmacological Approaches). Current Pharmaceutical Design. 20(35): 5507-5509.
    Organelle biogenesis is concomitant to organelle inheritance during cell division. It is necessary that organelles double their size and divide to give rise to two identical daughter cells. Mitochondrial biogenesis occurs ...
  • The mechanistic link between Arc/Arg3.1 expression and AMPA receptor endocytosis 

    Wall MJ and Correa SAL (2017) The mechanistic link between Arc/Arg3.1 expression and AMPA receptor endocytosis. Accepted for publication
    The activity-regulated cytoskeleton associated protein (Arc/Arg3.1) plays a key role in determining synaptic strength through facilitation of AMPA receptor (AMPAR) endocytosis. Although there is considerable data on the ...
  • Study of molecular structure, chemical reactivity and H-bonding interactions in the cocrystal of nitrofurantoin with urea 

    Khan E, Shukla A, Jadav N et al (2017) Study of molecular structure, chemical reactivity and H-bonding interactions in the cocrystal of nitrofurantoin with urea. New Journal of Chemistry. Accepted for publication.
    The cocrystal of nitrofurantoin with urea (C8H6N4O5)·(CH4N2O), a non-ionic supramolecular complex, has been studied. Nitrofurantoin (NF) is a widely used antibacterial drug for the oral treatment of infections of the urinary ...
  • Excavations at Old Scatness, Shetland, Volume 2: The Broch and Iron Age Village 

    Dockrill SJ, Bond JM, Turner VE et al (Eds) (2015) Excavations at Old Scatness, Shetland, Volume 2: The Broch and Iron Age Village. Shetland Heritage Publications: Lerwick.
    Excavations at Old Scatness Volume 2: The Broch and Iron Age Village, is the second title in the series from the extensive excavation project carried out at Old Scatness, following on from the publication of the first ...
  • Pseudo electron-deficient organometallics: limited reactivity towards electron-donating ligands 

    Pitto-Barry A, Lupan A, Zegke M et al (2017) Pseudo electron-deficient organometallics: limited reactivity towards electron-donating ligands. Dalton Transactions. Accepted for publication.
    Half-sandwich metal complexes are of considerable interest in medicine, material, and nanomaterial chemistry. The design of libraries of such complexes with particular reactivity and properties is therefore a major quest. ...
  • Neurodegenerative Diseases: Pathology, Mechanisms and Potential Therapeutic Targets 

    Beart P, Robinson M, Rattray M et al (Eds) (2017) Neurodegenerative Diseases: Pathology, Mechanisms, and Potential Therapeutic Targets. Advances in Neurobiology. Vol. 15. Springer International Publishing: Cham.Switzerland.
    Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration ...
  • Stem Cell Organoids in Primary Cultures of Human Non-Malignant and Malignant Colon 

    Tariq ST, Tahseen M, Hassan M et al (2017) Stem Cell Organoids in Primary Cultures of Human Non-Malignant and Malignant Colon. Journal of Molecular Biomarkers and Diagnosis. 8: 364.
    A sub-population of cells named cancer stem cells (CSCs) that initiate and promote tumour growth have been demonstrated to exist in several malignancies including colon carcinoma. The objective of our pilot study was to ...
  • Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells 

    Alharbi RA, Pandha HS, Simpson GR et al (2017) Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells. Oncotarget. Article in Press.
    The HOX genes encode a family of transcription factors that have key roles in both development and malignancy. Disrupting the interaction between HOX proteins and their binding partner, PBX, has been shown to cause apoptotic ...
  • The dynameomics entropy dictionary: a large-scale assessment of conformational entropy across protein fold space 

    Towse C, Akke M and Daggett V (2017) The dynameomics entropy dictionary: a large-scale assessment of conformational entropy across protein fold space. The Journal of Physical Chemistry B. 121(16): 3933-3945.
    Molecular dynamics (MD) simulations contain considerable information with regard to the motions and fluctuations of a protein, the magnitude of which can be used to estimate conformational entropy. Here we survey conformational ...
  • Pathway-dependent gold nanoparticle formation by biocatalytic self-assembly 

    Sahoo JK, Roy S, Javid N et al (2017) Pathway-dependent gold nanoparticle formation by biocatalytic self-assembly. Nanoscale. Article in Press.
    We report on the use of non-equillibrium biocatalytic self-assembly and gelation to guide the reductive synthesis of gold nanoparticles. We show that biocatalytic rates simultaneously dictate supramolecular order and ...
  • Development and Characterization of Acellular Porcine Pulmonary Valve Scaffolds for Tissue Engineering 

    Luo J, Korossis SA, Wilshaw S-P, Jennings LM, Fisher J and Ingham E (2014) Development and Characterization of Acellular Porcine Pulmonary Valve Scaffolds for Tissue Engineering. Tissue Engineering Part A. 20(21-22): 2963-2974.
    Currently available replacement heart valves all have limitations. This study aimed to produce and characterize an acellular, biocompatible porcine pulmonary root conduit for reconstruction of the right ventricular outflow ...
  • Gamma-irradiated human amniotic membrane decellularised with sodium dodecyl sulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells 

    Figueiredo GS, Bojic S, Rooney P, Wilshaw S-P, Connon CJ, et al (2017) Gamma-irradiated human amniotic membrane decellularised with sodium dodecyl sulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells. Acta Biomaterialia. 61: 124-133.
    The gold standard substrate for the ex vivo expansion of human limbal stem cells (LSCs) remains the human amniotic membrane (HAM) but this is not a defined substrate and is subject to biological variabil-ity and the potential ...
  • An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering 

    Zilic L, Garner PE, Yu T, Roman S, Haycock JW, Wilshaw S-P (2017) An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering. Journal of Anatomy. 227(3): 302–314.
    Current nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy ...
  • Decellularisation and histological characterisation of porcine peripheral nerves 

    Zilic L, Wilshaw S-P and Haycock JW (2017) Decellularisation and histological characterisation of porcine peripheral nerves. Biotechnology and Bioengineering.113(9): 2041–2053.
    Peripheral nerve injuries affect a large proportion of the global population, often causing significant morbidity and loss of function. Current treatment strategies include the use of implantable nerve guide conduits (NGC's) ...
  • Binding of bacteria to poly (N-isopropylacrylamide) modified with vancomycin: Comparison of behavior of linear and highly branched polymers 

    Teratanatorn P, Hoskins R, Swift T et al (2017) Binding of bacteria to poly (N-isopropylacrylamide) modified with vancomycin: Comparison of behavior of linear and highly branched polymers. Biomacromolecules. 18(9): 2887-2899.
    The behavior of a linear copolymer of N-isopropyl acrylamide with pendant vancomycin functionality was compared to an analogous highly branched copolymer with vancomycin functionality at the chain ends. Highly branched ...
  • Förster Resonance Energy Transfer across interpolymer complexes of poly(acrylic acid) and poly(acrylamide) 

    Swift T, Paul N, Swanson L et al (2017) Förster Resonance Energy Transfer across interpolymer complexes of poly(acrylic acid) and poly(acrylamide). Polymer. 123: 10-20.
    Interpolymer complexes of homopolymer macromolecules are often described as ‘laddered’ or ‘ribbon’ type structures. The proposition of the existence of these ladder structures seems to us not reasonable and here we examine ...

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