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  • Expanding the scope of the crystallization-driven self-assembly of polylactide-containing polymers 

    Pitto-Barry A, Kirby N, Dove AP et al (2014) Expanding the scope of the crystallizationdriven self-assembly of polylactide-containing polymers. Polymer Chemistry. 5(4): 1427-1436.
    We report the crystallization-driven self-assembly of diblock copolymers bearing a poly(L-lactide) block into cylindrical micelles. Three different hydrophilic corona-forming blocks have been employed: poly(4-acryloyl ...
  • Development and characterisation of a large diameter decellularised vascular allograft 

    Aldridge A, Desai A, Owston H et al (2018) Development and characterisation of a large diameter decellularised vascular allograft. Cell Tissue Bank. Accepted for publication.
    The aims of this study were to develop a biological large diameter vascular graft by decellularisation of native human aorta to remove the immunogenic cells whilst retaining the essential biomechanical, and biochemical ...
  • Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation 

    Sun L, Pitto-Barry A, Kirby N et al (2014) Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation. Nature Communications. 5(5746).
    Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved ...
  • Dual effect of thiol addition on fluorescent polymeric micelles: ON-to-OFF emissive switch and morphology transition 

    Mabire AB, Robin MP, Willcock H et al (2014) Dual effect of thiol addition on fluorescent polymeric micelles: ON-to-OFF emissive switch and morphology transition. Chemical Communications. 50(78): 11492-11495.
    The morphology transition from micelles to vesicles of a solution-state self-assembled block copolymer, containing a fluorescent dye at the core–shell interface, has been induced by an addition–elimination reaction using ...
  • Absolute Energy Level Positions in CdSe Nanostructures from Potential-Modulated Absorption Spectroscopy (EMAS) 

    Spittel D, Poppe J, Meerbach C et al (2018) Absolute Energy Level Positions in CdSe Nanostructures from Potential-Modulated Absorption Spectroscopy (EMAS). ACS Nano. Accepted for publication.
    Semiconductor nanostructures like CdSe quantum dots and colloidal nanoplatelets exhibit remarkable optical properties, making them interesting for applications in optoelectronics and photocatalysis. For both areas of ...
  • Characterising the growth in palliative care prescribing 2011-2015: Analysis of national medical and non-medical activity 

    Ziegler L, Bennett MI, Mulvey M et al (2018) Characterising the growth in palliative care prescribing 2011-2015: Analysis of national medical and non-medical activity. Palliative Medicine. Accepted for publication.
    The role of non-medical prescribers working in palliative care has been expanding in recent years and prescribers report improvements in patient care, patient safety, better use of health professionals’ skills and more ...
  • Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: Synthesis, stability, biocompatibility and potential use as peptide carriers 

    Umerska A, Paluch KJ, Santos Martinez M-J et al (2014) Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: Synthesis, stability, biocompatibility and potential use as peptide carriers. Journal of Biomedical Nanotechnology. 10(12): 3658-3673.
    This work investigates a new type of polyelectrolyte complex nanocarrier composed of hyaluronic acid (HA) and protamine (PROT). Small (approximately 60 nm) and negatively charged nanoparticles (NPs) with a polydispersity ...
  • Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life 

    Miranda BH, Charlesworth MR, Tobin DJ et al (2017) Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life. FASEB Journal. Accepted for publication.
    Male sex hormones-androgens-regulate male physique development. Without androgen signaling, genetic males appear female. During puberty, increasing androgens harness the hair follicle's unique regenerative ability to replace ...
  • Poly(acrylic acid) interpolymer complexes 

    Swift T, Seaton CC and Rimmer S (2017) Poly(acrylic acid) interpolymer complexes. Soft Matter. 13(46): 8736-8744.
    Interpolymer complex formation of poly(acrylic acid) with other macromolecules can occur via several mechanisms that vary depending on the pH. At low pH the protonated acid functional group can form bonds with both donor ...
  • Le Castellan (Istres, Bouches-du-Rhône) : resultats de prospections géophysique 

    Armit I, Horsley T and Marty F (2018) Le Castellan (Istres, Bouches-du-Rhône) : resultats de prospections géophysique. Documents d’Archéologie Méridionale. 39: 75-82. Accepted for publication.
    Two seasons of geophysical prospection (magnetic, resistance and ground-penetrating radar) were conducted at the Iron Age oppidum of Le Castellan, Istres, Bouches-du-Rhône, in order to determine the utility of these ...
  • In-process rheometry as a PAT tool for hot melt extrusion 

    Kelly AL, Gough T, Isreb M et al (2017) In-process rheometry as a PAT tool for hot melt extrusion. Drug Development and Industrial Pharmacy. Article in Press.
    Real time measurement of melt rheology has been investigated as a Process Analytical Technology (PAT) to monitor hot melt extrusion of an Active Pharmaceutical Ingredient (API) in a polymer matrix. A developmental API was ...
  • The critical role of oxidative stress in diethylstilbestrol induced male germ cell apoptosis 

    Habas K, Brinkworth MH and Anderson D (2017) The critical role of oxidative stress in diethylstilbestrol induced male germ cell apoptosis. In: Berhardt LV (Ed) Advances in Medicine and Biology. Vol 125. New York: Nova Science Publishers: 161-186.
  • An evaluation of DNA damage in human lymphocytes and sperm exposed to methyl methanesulfonate involving the regulation pathways associated with apoptosis 

    Habas K, Najafzadeh M, Baumgartner A et al (2017) An evaluation of DNA damage in human lymphocytes and sperm exposed to methyl methanesulfonate involving the regulation pathways associated with apoptosis. Chemosphere. 185: 709-716.
    Exposure to DNA-damaging agents produces a range of stress-related responses. These change the expression of genes leading to mutations that cause cell cycle arrest, induction of apoptosis and cancer. We have examined the ...
  • In vitro responses to known in vivo genotoxic agents in mouse germ cells 

    Habas K, Brinkworth MH and Anderson D (2017) In vitro responses to known in vivo genotoxic agents in mouse germ cells. Environmental and Molecular Mutagenesis. 58(2): 99-107.
    Genotoxic compounds have induced DNA damage in male germ cells and have been associated with adverse clinical outcomes including enhanced risks for maternal, paternal and offspring health. DNA strand breaks represent a ...
  • Diethylstilbestrol induces oxidative DNA damage, resulting in apoptosis of spermatogonial stem cells in vitro 

    Habas K, Brinkworth MH and Anderson D (2017) Diethylstilbestrol induces oxidative DNA damage, resulting in apoptosis of spermatogonial stem cells in vitro. Toxicology. 382: 117-121.
    The spermatogonial stem cells (SSCs) are the only germline stem cells in adults that are responsible for the transmission of genetic information from mammals to the next generation. SSCs play a very important role in the ...
  • The NHS Health Check programme: insights from a qualitative study of patients 

    Ismail H and Atkin K (2016) The NHS Health Check programme: insights from a qualitative study of patients. Health Expectations. 19(2): 345-355.
    To provide an insight into the process of patients receiving Health Checks and to determine the extent to which patients were supported to reduce the risks of developing cardiovascular disease through behaviour ...
  • Arrhythmia care co-ordinators: Their impact on anxiety and depression, readmissions and health service costs 

    Ismail H and Coulton S (2016) Arrhythmia care co-ordinators: Their impact on anxiety and depression, readmissions and health service costs. European Journal of Cardiovascular Nursing. 15(5): 355-362.
    In 2005, the UK Department of Health recommended that a new role, the arrhythmia care coordinator (ACC), be created to guide patients through the diagnosis and treatment for arrhythmia. The belief was that this would improve ...
  • Lessons learned from England’s Health Checks Programme: using qualitative research to identify and share best practice 

    Ismail H and Kelly S (2015) Lessons learned from England’s Health Checks Programme: using qualitative research to identify and share best practice. BMC Family Practice. 16: 144.
    This study aimed to explore the challenges and barriers faced by staff involved in the delivery of the National Health Service (NHS) Health Check, a systematic cardiovascular disease (CVD) risk assessment and management ...
  • Ethical tissue: a not-for-profit model for human tissue supply 

    Adams K and Martin S (2011) Ethical tissue: a not-for-profit model for human tissue supply. Cell and Tissue Banking. 12(1): 9-10.
    Following legislative changes in 2004 and the establishment of the Human Tissue Authority, access to human tissues for biomedical research became a more onerous and tightly regulated process. Ethical Tissue was established ...
  • Leading academic change: experiences of academic staff implementing team-based learning 

    Nelson M and Tweddell S (2017) Leading academic change: experiences of academic staff implementing team-based learning. RAISE: Student Engagement in Higher Education Journal. 1(2): 100-116.
    Team-based learning (TBL) is a collaborative learning model that shifts classroom time from a teacher-centred to student-centred approach. TBL emphasises accountability to learning, teamwork, immediate feedback, peer ...

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