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  • PublicationOpen Access
    Pharmaceutical supply chain resilience. An exploratory analysis of vulnerabilities and resilience strategies in the face of dynamic disruptions in the UK pharmaceutical supply chain
    (2019) Yaroson, Emilia V.; Breen, Liz; Hou, Jiachen; Sowter, Julie
    Pharmaceutical supply chains are susceptible to disruptions which impact on the operational and financial performance of firms as well as patient safety. This study aimed to explore why the Pharmaceutical Supply Chain (PSC) in the UK is susceptible to the impact of dynamic disruptions and examine how resilience strategies have were employed to reduce the effects of these disruptions. The Complex Adaptive System (CAS) theory was used as a framework in an exploratory research design using mixed-methods. The qualitative data were gathered through 23 semi-structured interviews with key supply chain actors across the PSC in the UK to explore their experiences. The findings from these semi-structured interviews were used to develop a survey which was distributed to a broader spectrum of supply chain actors where the final sample from the survey was (n=106). The data were triangulated to discuss the research findings. The initial results revealed power, conflict and complexities as drivers of vulnerabilities in the PSC. Antecedents for building resilience strategies included visibility, flexibility and joint decision making as recovery strategies and resource sharing as the resistance strategy. CAS provided a systemic approach to understanding PSC resilience rather than in parts. In doing so, it took into consideration the various elements that make up the entire system. Thus, vulnerabilities and resilience strategies were outcomes of the interactions between supply chain actors. The findings demonstrated that CAS, as a theory, provided a framework that was beneficial in exploring and gaining insights into PSC resilience. Also, by combining the two datasets (interviews and survey), an original output was proposed -the Pharmaceutical Supply Chain Resilience Framework (PSCRF)- which was used to recommend resilience strategies suitable for mitigating disruptions in the PSC.
  • PublicationOpen Access
    An intelligent edge computing based semantic gateway for healthcare systems interoperability and collaboration
    (IEEE, 2018-09) Sigwele, Tshiamo; Hu, Yim Fun; Ali, M.; Hou, Jiachen; Susanto, Misfa; Fitriawan, H.
    The use of Information and Communications Technology (ICTs) in healthcare has the potential of minimizing medical errors, reducing healthcare cost and improving collaboration between healthcare systems which can dramatically improve the healthcare service quality. However interoperability within different healthcare systems (clinics/hospitals/pharmacies) remains an issue of further research due to a lack of collaboration and exchange of healthcare information. To solve this problem, cross healthcare system collaboration is required. This paper proposes a conceptual semantic based healthcare collaboration framework based on Internet of Things (IoT) infrastructure that is able to offer a secure cross system information and knowledge exchange between different healthcare systems seamlessly that is readable by both machines and humans. In the proposed framework, an intelligent semantic gateway is introduced where a web application with restful Application Programming Interface (API) is used to expose the healthcare information of each system for collaboration. A case study that exposed the patient's data between two different healthcare systems was practically demonstrated where a pharmacist can access the patient's electronic prescription from the clinic.
  • PublicationOpen Access
    The role of power-based behaviours in pharmaceutical supply chain resilience
    (2023-04-28) Yaroson, Emilia V.; Breen, Liz; Hou, Jiachen; Sowter, Julie
    Purpose This study explored the effect of power-based behaviours on pharmaceutical supply chain (PSC) resilience. Design/methodology/approach This study used a mixed-method approach to explore the role of power-based behaviours in PSC resilience. Qualitative interviews from 23 key PSC stakeholders, followed by thematic analysis, revealed the underlying perceptions regarding PSC resilience. Quantitative propositions were then developed based on the themes adopted from PSC resilience literature and the qualitative findings. These were tested via a survey questionnaire administered to 106 key stakeholders across the various levels in the PSC. Structural equation modelling with partial least squares was used to analyse the data. Findings The data analysed identified proactive and reactive strategies as resilience strategies in the PSC. However, power-based behaviours represented by quota systems, information and price control influenced these resilience strategies. From a complex adaptive system (CAS) perspective, we found that when power-based behaviours were exhibited, the interactions between PSC actors were mixed. There was a negative influence on reactive strategies and a positive influence on proactive strategies. Our analysis also showed that PSC complexities measured by (stringent regulations, long lead times and complex production) moderated the effect of power-based behaviour on reactive strategies. Thus, the negative impact of power-based behaviours on reactive strategies stemmed from PSC complexities. Research implications Our research particularly reveals the role of power-based behaviours in building PSC resilience. By evaluating the nexus from a CAS perspective, the analysis considered powerbased behaviours and the moderating role of PSC complexities in developing resilience strategies. The study considers the interactions of PSC actors. It shows that power asymmetry is a relational concept that inhibits the efficacy of reactive strategies. This study thus advocates the importance of power in achieving a more resilient PSC from a holistic perspective by highlighting the importance of the decision-making process among supply chain partners. Our findings are particularly relevant if PSC resilience is viewed as a complex adaptive system (CAS). All the interactions and decision-making processes affect outcomes due to their inherent complexities. Although this study focused on the PSC, its implications could be extended to other SCs (supply chains). Practical implications We identified that power-based behaviours influenced resilience strategies. It was detrimental to reactive strategies due to the complexities of the PSC but beneficial to proactive strategies through resource-sharing. PSC actors are therefore encouraged to pursue proactive strategies as this may aid in mitigating the impact of disruptions. However, power-based behaviours bred partner dissatisfaction. This dissatisfaction may occur even within strategic alliances indicating that power could be detrimental to proactive strategies. Therefore, it is pertinent to identify conditions that lead to dissatisfaction when pursuing strategic partnerships. This study provides insight into actual behaviours influencing resilience and quantifies their effects on the PSC. These insights will be valuable for all supply chain partners wanting to improve their resilience strategies. Originality/value Previous PSC management and resilience studies have not examined the role of power in building resilience in the PSC. This paper thus provides a unique contribution by identifying the role of power in PSC resilience, offers empirical evidence and a novel theoretical perspective for future practice and research in building PSC resilience strategies.
  • PublicationRestricted
    Examining the impact of resilience strategies in mitigating medicine shortages in the United Kingdom's (UK) pharmaceutical supply chain (PSC)
    (2023) Yaroson, E.V.; Breen, Liz; Hou, Jiachen; Sowter, Julie
    Purpose Medicine shortages have a detrimental impact on stakeholders in the pharmaceutical supply chain (PSC). Existing studies suggest that building resilience strategies can mitigate the effects of these shortages. As such, this research aims to examine whether resilience strategies can reduce the impact of medicine shortages in the United Kingdom's (UK) PSC. Design/methodology/approach A sequential mixed-methods approach that involved qualitative and quantitative research enquiry was employed in this study. The data were collected using semi-structured interviews with 23 key UK PSC actors at the qualitative stage. During the quantitative phase, 106 respondents completed the survey questionnaires. The data were analysed using partial least square-structural equation modelling (PLS-SEM). Findings The results revealed that reactive and proactive elements of resilience strategies helped tackle medicine shortages. Reactive strategies increased relational issues such as behavioural uncertainty, whilst proactive strategies mitigated them. Practical implications The findings suggest that PSC managers and decision-makers can benefit from adopting structural flexibility and proactive strategies, which are cost-effective measures to tackle medicine shortages. Also engaging in strategic alliances as a proactive strategy mitigates relational issues that may arise in a complex supply chain (SC). Originality/value This study is the first to provide empirical evidence of the impact of resilience strategies in mitigating medicine shortages in the UK's PSC.
  • PublicationOpen Access
    Sustainability in supply chain management practices in least developed countries: A case of SMEs in Zambian mining sector
    (University of Bradford) Manchisi, Roy; Barber, Kevin D.; Breen, Liz; Hou, Jiachen
    The focus of this study is to explore the sustainability practices of SME suppliers as influenced by the stakeholders in the mining SC in Zambia. The study aims to provide the policymakers and senior managers of focal firms by developing a detailed framework that helps in examining the SME environment with regard to sustainability practices and formulate measures to increase their sustainability performance to decision making. This qualitative research used 50 semi-structured interviews in addressing the research objective. Interviews undertaking with cross section of stakeholders and using content analysis, the findings revealed that SMEs engage in sustainable practices when working with mining firms but disengage when working with non-mining firms. The findings further revealed the mechanisms employed by SC members in extending sustainability practices to direct and indirect suppliers (mainly informal SMEs) from focal firms. In so doing, the findings highlighted the role of first-tier suppliers as a bridge between the focal firms and sub-suppliers in disseminating sustainability practices. Besides revealing the drivers and barriers to sustainability, the research revealed the mechanisms for mitigating the barriers in order to increase the volume of SME suppliers adopting sustainable practices. This research has several contributions to both academia and practice. The main contribution to academia is a stakeholder framework, which provides a systematic mechanism of examining the sustainability phenomenon. Thus, presenting a theoretical approach for analysing and understanding sustainability practices of SMEs in a developing country context. The main contribution to practice is the production of tools that support practitioners to analyse and better comprehend the relationships in the SMEs sector and by identifying the key stakeholders that support the SMEs.