Solid-phase synthesis of C-terminal thio-linked glycopeptides
Falconer, Robert A. Malkinson, J.P.
Falconer, Robert A.
Malkinson, J.P.
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2002
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Abstract
A solid-phase Mitsunobu reaction between a resin-bound 1-thiosugar and an N-Fmoc protected amino alcohol was successfully employed for thio-linked glycopeptide synthesis. Facile cleavage and deprotection in one step afforded the target glycopeptide in good yield and purity.
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Falconer, R.A. and Malkinson, J.P. (2002). Solid-phase synthesis of C-terminal thio-linked glycopeptides. Tetrahedron Letters. Vol. 43, No. 52, pp. 4549-9552.
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