Vibrational spectroscopic study of salbutamol hemisulphate
Ali, H.R.H. Edwards, Howell G.M. Kendrick, John Scowen, Ian J.
Ali, H.R.H.
Edwards, Howell G.M.
Kendrick, John
Scowen, Ian J.
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01/01/2009
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Abstract
Salbutamol hemisulphate is a relatively selective ß2-adrenergic agonist and is used as a bronchodilator. In this work, we present a detailed vibrational spectroscopic investigation of salbutamol hemisulphate using mid-infrared and near-infrared Fourier-transform (NIR-FT) Raman spectroscopies. These data are supported by quantum chemical calculations, which allow us to characterise the vibrational spectra of this compound reasonably. As such, this study could be viable for examining the way in which this drug interacts with its target molecules.
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Ali HRH, Edwards HGM, Kendrick J and Scowen IJ (2009) Vibrational spectroscopic study of salbutamol hemisulphate. Drug Testing and Analysis. 1(1): 51-56.
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