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Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture
Khaghani, Seyed A. ; Sefat, Farshid ; ; Rehman, R. ; Soon, Chin Fhong ; Akbarova, G.
Khaghani, Seyed A.
Sefat, Farshid
Rehman, R.
Soon, Chin Fhong
Akbarova, G.
Publication Date
2016
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© 2016 The Authors. Published by eCM. With kind permission of full reproduction from eCM journal (www.ecmjournal.org). Founded by scientists for the benefit of Science rather than profit. DOI: http://dx.doi.org/10.3791/51826.
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Abstract
Regeneration of a damaged or non-functioning tissue requires adhesion of cells to their extracellular matrix (ECM). Thus the investigation of the level of synthesised cell adhesion molecules (CAMs) in cell culture systems play major roles in cell and tissue engineering. Adhesion of chondrocyte to a collagen type-II rich matrix, is dependent on cell adhesion molecules (CAMs) and integrins and cells adhere to ECM through integrins.
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Khaghani SA, Sefat F, Youseffi M, Rehman R, Soon CF and Akbarova G (2016) Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture. European Cells and Materials, August 2016, UCL, London, UK. In: European Cells and Materials, Vol 32, Suppl 4, p 56.
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