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An investigation of the relationship between the structure and function of the myopic eye. Correlating the optical, functional and structural aspects of ametropia in young adult humans.

Ehsaei, Asieh
Publication Date
2013-04-09
End of Embargo
Supervisor
Mallen, Edward A.H.
Chisholm, Catharine M.
Pacey, Ian E.
Keywords
Myopia, Emmetropia, Visual performance, Ocular biometry, Peripheral refraction.
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Creative Commons License
The University of Bradford theses are licenced under a Creative Commons Licence.
Peer-Reviewed
Open Access status
Accepted for publication
Institution
University of Bradford
Department
Bradford School of Optometry and Vision Science
Awarded
2012
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Complete PhD thesis, Asieh Ehsaei (1).pdf
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Abstract
The increasing prevalence of myopia over the past few decades and its association with potential ocular complications make myopia an important research topic. The present work is concerned with the structural and functional characteristics of a group of myopic and emmetropic individuals. The technical experiments in this work investigated firstly the effect of instrument alignment on peripheral refraction measurements and revealed that the corneal vertex was an acceptable alignment position of the Shin-Nippon NVision-K 5001 autorefractor, allowing consistent alignment with other instruments used in this research. Secondly, spectacles could be used to provide comparable vision to contact lenses in the visual performance studies. In the main experimental parts of this work, visual performance and multiple aspects of ocular structure were assessed across a wide range of eccentricities along the horizontal and vertical meridians within the same eyes. The structural properties of the myopic eye were measured through central and peripheral autorefraction, and through cornea to retina dimensions using non-contact biometry. In addition, the central and peripheral resolution acuities of myopic and emmetropic eyes for high and low contrast levels were investigated. Our structural and functional measurements revealed relatively prolate myopic eyes with reduced high contrast resolution acuity, compared to emmetropic eyes. Moreover, multiple regression analyses were performed at the fovea and outermost retinal eccentricities common to all core experiments but revealed no strong relationship between the structure and function of the myopic eye. Finally, regarding asymmetry, the nasal and superior retinae were found to be longer and to perform better in comparison to the temporal and superior retinae respectively.
URI
http://hdl.handle.net/10454/5524
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Type
Thesis
Qualification name
PhD
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