Design, Synthesis and Biological Evaluation of Chemical Probes Incorporating Aldehyde Dehydrogenase (ALDH) Recognition Motifs and Fluorescent Properties. An Investigation Towards the Development of ALDH-Affinic Fluorophores for Hypoxia Cell Tracking

Pors, KlausIbrahim, Ali I.M.2025-04-302020-11-262025-04-302017https://bradscholars.brad.ac.uk/handle/10454/18179.2en<a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><img alt="Creative Commons License" style="border-width:0" src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" /></a><br />The University of Bradford theses are licenced under a <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/">Creative Commons Licence</a>.Aldehyde dehydrogenase (ALDH)ALDH7A1CancerHypoxiaComputational modellingAnthraquinoneFluorophoreALDH inhibitorDesign, Synthesis and Biological Evaluation of Chemical Probes Incorporating Aldehyde Dehydrogenase (ALDH) Recognition Motifs and Fluorescent Properties. An Investigation Towards the Development of ALDH-Affinic Fluorophores for Hypoxia Cell Trackingdoctoral