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dc.contributor.authorGrant, Colin A.*
dc.contributor.authorTwigg, Peter C.*
dc.contributor.authorBaker, Richard*
dc.contributor.authorTobin, Desmond J.*
dc.date.accessioned2016-10-14T13:45:38Z
dc.date.available2016-10-14T13:45:38Z
dc.date.issued2015-05-20
dc.identifier.citationGrant CA, Twigg PC, Baker R and Tobin DJ (2015) Tattoo ink nanoparticles in skin tissue and fibroblasts. Beilstein Journal of Nanotechnology. 6: 1183-1191.en_US
dc.identifier.urihttp://hdl.handle.net/10454/9922
dc.descriptionYesen_US
dc.description.abstractTattooing has long been practised in various societies all around the world and is becoming increasingly common and widespread in the West. Tattoo ink suspensions unquestionably contain pigments composed of nanoparticles, i.e., particles of sub-100 nm dimensions. It is widely acknowledged that nanoparticles have higher levels of chemical activity than their larger particle equivalents. However, assessment of the toxicity of tattoo inks has been the subject of little research and ink manufacturers are not obliged to disclose the exact composition of their products. This study examines tattoo ink particles in two fundamental skin components at the nanometre level. We use atomic force microscopy and light microscopy to examine cryosections of tattooed skin, exploring the collagen fibril networks in the dermis that contain ink nanoparticles. Further, we culture fibroblasts in diluted tattoo ink to explore both the immediate impact of ink pigment on cell viability and also to observe the interaction between particles and the cells.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.3762/bjnano.6.120en_US
dc.rights© 2015 Grant et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (http://www.beilsteinjournals. org/bjnano) The definitive version of this article is the electronic one which can be found at: doi: http://dx.doi.org/10.3762/bjnano.6.120en_US
dc.subjectAtomic force microscopy (AFM); Dermis; Nanoparticles; Skin; Tattoo inken_US
dc.titleTattoo ink nanoparticles in skin tissue and fibroblastsen_US
dc.status.refereedYesen_US
dc.date.Accepted2015-04-22
dc.date.application2015-05-20
dc.typeArticleen_US
dc.type.versionPublished versionen_US
refterms.dateFOA2018-07-27T01:37:35Z


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