Show simple item record

dc.contributor.authorHadi, M.A.*
dc.contributor.authorAlldred, David P.*
dc.contributor.authorBriggs, M.*
dc.contributor.authorMunyombwe, T.*
dc.date.accessioned2016-10-10T16:02:58Z
dc.date.available2016-10-10T16:02:58Z
dc.date.issued2014
dc.identifier.citationHadi MA, Alldred DP, Briggs M et al (2014) Effectiveness of pharmacist-led medication review in chronic pain management: systematic review and meta-analysis. Clinical Journal of Pain. 30(11): 1006-1014.
dc.identifier.urihttp://hdl.handle.net/10454/9841
dc.descriptionNo
dc.description.abstractThe objective of this article was to evaluate the effectiveness of pharmacist-led medication review in chronic pain management. Six electronic databases (Medline, Embase, PsycInfo, CINHAL, CENTRAL, International Pharmaceutical Abstracts) reference lists of retrieved articles and relevant websites were searched for randomized controlled trials published in the English language involving adults with chronic pain. Studies were included if one of the intervention arms had received pharmacist-led medication review independently or as part of a multidisciplinary intervention. Risk of bias was assessed for all the included studies. The search strategy yielded 583 unique articles including 5 randomized controlled trials. Compared with control, meta-analysis showed that participants in the intervention group had: a 0.8-point reduction in pain intensity on a 0 to 10 numerical rating scale at 3 months [95% confidence interval (CI), -1.28 to -0.36] and a 0.7-point reduction (95% CI, -1.19 to -0.20) at 6 months; a 4.84 point (95% CI, -7.38 to -2.29) and -3.82 point (95% CI, -6.49 to -1.14) improvement in physical functioning on a 0- to 68-point function subscale of Western Ontario and McMaster Universities Osteoarthritis Index at 3 and 6 months, respectively; and a significant improvement in patient satisfaction equivalent to a "small to moderate effect." Pharmacist-led medication review reduces pain intensity and improves physical functioning and patient satisfaction. However, the clinical significance of these findings remain uncertain due to small effect size and nature of reported data within clinical trials that limits recommendation of wider clinical role of pharmacist in chronic pain management.
dc.relation.isreferencedbyhttp://dx.doi.org/10.1097/AJP.0000000000000063
dc.subjectPharmacist; Medication review; Chronic pain; Systematic review; Pain intensity; Physical functioning; Adverse effects
dc.titleEffectiveness of pharmacist-led medication review in pain management: systematic review and meta-analysis
dc.status.refereedYes
dc.typeArticle
dc.type.versionNo full-text available in the repository


This item appears in the following Collection(s)

Show simple item record