Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

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Publication date
2013-11-20Keyword
Acetylation; Cell line
; Cell survival
; Gene expression regulation
; Gene knockdown techniques
; HCT116 cells
; Humans
; MCF-7 cells
; Neoplasms
; Nuclear proteinsy
; RNA interference
; Sirtuin 1
; Transcription factors
; Tumor suppressor protein p53
; Active regulator of SIRT1
; p53 acetylation
; Regulation of SIRT1
Rights
(c) 2013 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (https://creativecommons.org/licenses/by/4.0/)Peer-Reviewed
Yes