Synthesis and biological evaluation of N-cyanoalkyl-, Naminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents

Publication date
2016-11-01Author
Sola, I.Artigas, A.
Taylor, M.C.
Perez-Areales, F.J.
Viayna, E.
Clos, M.V.
Perez, B.
Wright, Colin W.
Kelly, J.M.
Muñoz-Torrero, D.
Keyword
4-Aminoquinolines; Side chain modification; Guanidines; Antitrypanosomal agents; Brain permeabilityRights
(c) 2016 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)Peer-Reviewed
Yes