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    The changing landscape of cancer drug discovery: a challenge to the medicinal chemist of tomorrow

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    Publication date
    2009-11
    Author
    Pors, Klaus
    Goldberg, F.W.
    Leamon, C.P.
    Rigby, A.C.
    Snyder, S.A.
    Falconer, Robert A.
    Keyword
    Cancer drug discovery; Medicinal chemistry; Chemical biology; Diversity-oriented synthesis; EPSRC; Government funding; NCI
    Peer-Reviewed
    Yes
    
    Metadata
    Show full item record
    Abstract
    Since the development of the first cytotoxic agents, synthetic organic chemistry has advanced enormously. The synthetic and medicinal chemists of today are at the centre of drug development and are involved in most, if not all, processes of drug discovery. Recent decreases in government funding and reformed educational policies could, however, seriously impact on drug discovery initiatives worldwide. Not only could these changes result in fewer scientific breakthroughs, but they could also negatively affect the training of our next generation of medicinal chemists.
    URI
    http://hdl.handle.net/10454/8821
    Version
    published version paper
    Citation
    Pors K, Goldberg FW, Leamon CP, Rigby AC, Snyder SA, Falconer RA (2009) The changing landscape of cancer drug discovery: a challenge to the medicinal chemist of tomorrow. Drug Discovery Today, 14 (21/22): 1045-50.
    Link to publisher’s version
    http://www.sciencedirect.com/science/article/pii/S1359644609002323
    Type
    Article
    Collections
    Life Sciences Publications

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