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dc.contributor.authorOgunmefun, G.*
dc.contributor.authorHardy, Maryann L.*
dc.contributor.authorBoynes, Stephen*
dc.date.accessioned2016-03-17T15:41:48Z
dc.date.available2016-03-17T15:41:48Z
dc.date.issued2016
dc.identifier.citationOgunmefun G, Hardy ML and Boynes S (2016) Is magnetic resonance imaging a viable alternative to ultrasound as the primary imaging modality in the diagnosis of paediatric appendicitis? A systematic review. Radiography. Accepted for publication 2nd Jan 2016.en_US
dc.identifier.urihttp://hdl.handle.net/10454/7934
dc.descriptionYesen_US
dc.description.abstractBackground: Appendicitis is the most common cause of acute abdominal pain requiring surgical intervention in paediatric patients. Ultrasound is generally the diagnostic imaging modality of choice, followed by CT, where paediatric appendicitis is suspected. However, high operator dependency and diagnostic restrictions related to anatomical and clinical presentation may limit consistency of application. This paper explores whether MRI is a viable alternative to ultrasound as the primary imaging modality. Method: A systematic review of the literature was undertaken. A search of Medline, Cinahl, PubMed Central and Google Scholar was undertaken supplemented by a review of reference lists, author searching and review of NICE evidence base for existing guidelines. Included studies were assessed for bias using the QUADAS-2 quality assessment tool and data were extracted systematically using a purposefully designed electronic data extraction proforma. Results: Seven studies were included in final review. The age range of participants extended from 0 to 19 years. Only one study with a patient age range of 0e14 used sedation. Sensitivity estimates from the included studies ranged from 92% to 100% while specificity ranged from 89% to 100%. A significant variation in the number and type of sequences was noted between the studies. Conclusion: MRI offers high sensitivity and specificity comparable to contrast enhanced CT and greater than ultrasound as reported in the literature. Where accessibility is not a restriction, MRI is a viable alternative to ultrasound in the assessment and diagnosis of paediatric appendicitis. Clinical practice recommendations have been provided to facilitate the translation of evidence into practice.en_US
dc.language.isoenen_US
dc.rights© 2016 Elsevier. Reproduced in accordance with the publisher's self-archiving policy. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectChild paediatric appendicitis; Magnetic resonance imaging (MRI)en_US
dc.titleIs magnetic resonance imaging a viable alternative to ultrasound as the primary imaging modality in the diagnosis of paediatric appendicitis? A systematic reviewen_US
dc.status.refereedYesen_US
dc.date.Accepted2016-01-02
dc.typeArticleen_US
dc.type.versionAccepted Manuscripten_US
dc.identifier.doihttps://doi.org/10.1016/j.radi.2016.01.001
refterms.dateFOA2017-03-02T00:00:00Z


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