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dc.contributor.authorWalters, Elizabeth R.*
dc.contributor.authorLesk, Valerie E.*
dc.date.accessioned2016-02-22T12:56:55Z
dc.date.available2016-02-22T12:56:55Z
dc.date.issued2016
dc.identifier.citationWalters ER and Lesk VE (2016) The effect of prior caffeine consumption on neuropsychological test performance: a placebo-controlled study. Dementia and Geriatric Cognitive Disorders. Article in Press.en_US
dc.identifier.urihttp://hdl.handle.net/10454/7802
dc.descriptionYesen_US
dc.description.abstractBackground: The aim of this study was to investigate whether the prior consumption of 200mg of pure caffeine affected neuropsychological test scores in a group of elderly participants aged over 60 years. Method: Using a double blind placebo vs. caffeine design, participants were randomly assigned to receive 200mg of caffeine or placebo. A neuropsychological assessment testing the domains of general cognitive function, processing speed, semantic memory, episodic memory, executive function, working memory and short-term memory was carried out. Results: Significant interaction effects between age, caffeine and scores of executive function and processing speed were found; participants who had received caffeine showed a decline in performance with increasing age. This effect was not seen for participants who received placebo. Conclusion: The results highlight the need to consider and control prior caffeine consumption when scoring neuropsychological assessments in the elderly which is important for accuracy of diagnosis and corresponding normative data.en_US
dc.language.isoenen_US
dc.rights(c) 2016 S. Karger AG. Full-text reproduced in accordance with the publisher's self-archiving policy.en_US
dc.subjectCaffeine; Neuropsychological testing; Alzheimer's disease; Early diagnosis; Aging; Executive function; Placebo-controlleden_US
dc.titleThe effect of prior caffeine consumption on neuropsychological test performance: a placebo-controlled studyen_US
dc.status.refereedYesen_US
dc.date.Accepted2015-12-15
dc.typeArticleen_US
dc.type.versionfinal draft paperen_US
refterms.dateFOA2018-07-25T12:37:32Z


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