Show simple item record

dc.contributor.authorLister, L.J.*
dc.contributor.authorSuheimat, M.*
dc.contributor.authorVerkicharla, P.K.*
dc.contributor.authorMallen, Edward A.H.*
dc.contributor.authorAtchison, D.A.*
dc.date.accessioned2016-01-27T14:27:50Z
dc.date.available2016-01-27T14:27:50Z
dc.date.issued2016
dc.identifier.citationLister LJ, Suheimat M, Verkicharla PK, Mallen EAH and Atchison DA (2016) Influence of gravity on ocular lens position. Investigative Ophthalmology and Visual Science. 57: 1885-1891.en_US
dc.identifier.urihttp://hdl.handle.net/10454/7728
dc.descriptionyesen_US
dc.description.abstractPurpose: To determine whether human ocular lens position is influenced by gravity. Methods: Anterior chamber depth and lens thickness were determined with a Haag-Streit Lenstar LS900 for right eyes of participants in two age groups, with a young group of 13 participants aged 18 to 21 years (mean 21 years, SD 1 year) and an older group of 10 participants aged 50 to 63 years (58 years, 4 years). There were two sessions for each participant separated by at least 48 hours, with one session for the usual upright head position and one session for a downwards head position. In a session, testing was done for minimum accommodation followed by testing at maximum accommodation. A drop of 2% pilocarpine nitrate was instilled, and testing was repeated after 30 minutes under minimum and maximum accommodation conditions. Results: Gravity, manipulated through head posture, affected anterior chamber depth for both young adult and older adult groups but mean effects were only small, ranging from 0.04 to 0.12mm, and for the older group required the instillation of an accommodation-stimulating drug. Gravity had a weakly significant effect on lens thickness for the young group without accommodation or a drug, but the effect was small at 0.04±0.06mm (mean±SD, p = 0.04). Conclusion: There is a small but real effect of gravity on crystalline lens position, manifested as reduction in anterior chamber depth at high levels of accommodative effort with the head in a downwards position. This provides evidence of the ability of zonules to slacken during strong accommodation.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1167/iovs.15-18533en_US
dc.rights© 2016 ARVO. Reproduced in accordance with the publisher's self-archiving policy.en_US
dc.subjectAccommodation, Anterior chamber depth, Gravity, Lens, Human ocular lens positionen_US
dc.titleInfluence of gravity on ocular lens position.en_US
dc.status.refereedyesen_US
dc.date.Accepted2016-01-13
dc.typeArticleen_US
dc.type.versionPublished versionen_US
refterms.dateFOA2018-07-25T15:14:11Z


Item file(s)

Thumbnail
Name:
Lister et al IOVS accepted version ...
Size:
604.5Kb
Format:
PDF
Description:
Keep suppressed - original final ...
Thumbnail
Name:
i1552-5783-57-4-1885.pdf
Size:
890.2Kb
Format:
PDF
Description:
Main article

This item appears in the following Collection(s)

Show simple item record