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dc.contributor.authorSharif, Mhd Saeed*
dc.contributor.authorQahwaji, Rami S.R.*
dc.contributor.authorShahamatnia, E.*
dc.contributor.authorAlzubaidi, R.*
dc.contributor.authorIpson, Stanley S.*
dc.contributor.authorBrahma, A.*
dc.date.accessioned2016-01-18T15:25:01Z
dc.date.available2016-01-18T15:25:01Z
dc.date.issued2015-12
dc.identifier.citationSharif MS, Qahwaji RSR, Shahamatnia E, Alzubaidi R, Ipson SS and Brahma A (2015) An efficient intelligent analysis system for confocal corneal endothelium images. Computer Methods and Programs in Biomedicine. 122(3): 421-436.en_US
dc.identifier.urihttp://hdl.handle.net/10454/7683
dc.descriptionYesen_US
dc.description.abstractA confocal microscope provides a sequence of images of the corneal layers and structures at different depths from which medical clinicians can extract clinical information on the state of health of the patient’s cornea. Hybrid model based on snake and particle swarm optimisation (S-PSO) is proposed in this paper to analyse the confocal endothelium images. The proposed system is able to pre-process (quality enhancement, noise reduction), detect the cells, measure the cell density and identify abnormalities in the analysed data sets. Three normal corneal data sets acquired using confocal microscope, and two abnormal endothelium images associated with diseases have been investigated in the proposed system. Promising results are achieved and the performance of this system are compared with the performance of two morphological based approaches. The developed system can be deployed as clinical tool to underpin the expertise of ophthalmologists in analysing confocal corneal images.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1016/j.cmpb.2015.09.003en_US
dc.rights(c) 2015 Elsevier Ireland Ltd. Full-text reproduced in accordance with the publisher's self-archiving policy.en_US
dc.subjectConfocal microscope; Cornea; Endothelium layer; Snake; Particle Swarm Optimisationen_US
dc.titleAn efficient intelligent analysis system for confocal corneal endothelium imagesen_US
dc.status.refereedYesen_US
dc.date.Accepted2015-09-01
dc.typeArticleen_US
dc.type.versionAccepted Manuscripten_US
refterms.dateFOA2018-07-25T12:55:12Z


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