Development of in vitro models of invasion for the pharmacological investigation of small molecule inhibitors of tumour progression. Development and validation of a 3-dimensional tumour spheroid invasion model to evaluate the pharmacological effects of novel small molecule β3 integrin antagonists.
AuthorZraikat, Manar Saleh Ali
SupervisorShnyder, Steven D.
Phillips, Roger M.
KeywordCancer, Invasion, Migration, Integrins, Spheroids, Transwells, Pharmacology, Metastasis, Drug screening
The University of Bradford theses are licenced under a Creative Commons Licence.
InstitutionUniversity of Bradford
DepartmentInstitute of Cancer Therapeutics