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dc.contributor.authorWright, Colin W.*
dc.date.accessioned2015-10-08T11:30:56Z
dc.date.available2015-10-08T11:30:56Z
dc.date.issued2015-10
dc.identifier.citationWright C W (2015) Searching for new treatments of malaria. In: Heinrich M and Jager A K, Ethnopharmacology. Chichester: John Wiley & Sons Ltd. 123-134.
dc.identifier.urihttp://hdl.handle.net/10454/7418
dc.descriptionNo
dc.description.abstractThe aim of this chapter is to illustrate some current developments in natural product-derived antimalarial drugs. Traditional medicines have provided two of our most important antimalarial drugs (quinine and artemisinin) and have the potential to provide many novel antimalarial lead compounds of which several examples will be discussed. In addition, well- known natural antimalarials such as artemisinin continue to be an important focus of research and there is also increasing interest in investigating natural product sources that have not been traditionally used as antimalarials such as marine species of plants and animals. Assays based on specific malaria parasite targets such as thioredoxin reductase and heat shock protein have been employed to screen extracts and/or compounds and these have resulted in the identification of a number of potentially interesting antiplasmodial agents. However, since many victims of malaria are unable to afford antimalarial drugs, another approach adopted by some charities/NGO’s is to encourage people to grow their own medicinal plants such as Artemisia annua; some recent studies on this theme will be discussed.
dc.language.isoen
dc.subjectMalaria
dc.subjectAntimalarial drugs
dc.subjectTreatment
dc.subjectNatural products
dc.subjectDrug development
dc.subjectAntiplasmodial agents
dc.titleSearching for new treatments of malaria
dc.status.refereedNo
dc.typeBook chapter
dc.type.versionNo full-text in the repository
dc.identifier.doihttps://doi.org/10.1002/9781118930717.ch12
dc.openaccess.statusclosedAccess


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