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dc.contributor.authorMurphy, S.A.*
dc.contributor.authorNicolaou, Anna*
dc.date.accessioned2015-06-15T14:15:07Z
dc.date.available2015-06-15T14:15:07Z
dc.date.issued2013
dc.identifier.citationMurphy SA and Nicolaou A ( 2013) Lipidomics applications in health, disease and nutrition research. Molecular Nutrition and Food Research. 57(8): 1336-1346.en_US
dc.identifier.urihttp://hdl.handle.net/10454/7249
dc.descriptionNoen_US
dc.description.abstractThe structural and functional diversity of lipids accounts for their involvement into a wide range of homeostatic processes and disease states, including lifestyle-related diseases as well as genetic conditions. Challenges presented by this diversity have been addressed to a great extent by the development of lipidomics, a platform that makes possible the detailed profiling and characterisation of lipid species present in any cell, organelle, tissue or body fluid, and allows for a wider appreciation of the biological role of lipid networks. Progress in the field of lipidomics has been greatly facilitated by recent advances in MS and includes a range of analytical platforms supporting applications spanning from qualitative and quantitative assessment of multiple species to lipid imaging. Here we review these MS techniques currently in routine use in lipidomics, alongside with new ones that have started making an impact in the field. Recent applications in health, disease and nutrition-related questions will also be discussed with a view to convey the importance of lipidomics contributions to biosciences and food technology.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1002/mnfr.201200863en_US
dc.subjectBioactive lipids; Fatty acids; Food technology; Mass Spectrometry; MS; Phospholipidsen_US
dc.titleLipidomics applications in health, disease and nutrition researchen_US
dc.status.refereedyesen_US
dc.typeArticleen_US
dc.type.versionNo full-text available in the repositoryen_US


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