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    Gene Regulation at a Distance: Higher-Order Chromatin Folding and the Coordinated Control of Gene Transcription at the Epidermal Differentiation Complex Locus

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    Publication date
    2014
    Author
    Fessing, Michael Y.
    Keyword
    Gene regulation; Higher-order chromatin folding; Gene transcription; Gene regulatory elements; Epidermis; Epidermal Differentiation Complex Locus
    Peer-Reviewed
    yes
    
    Metadata
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    Abstract
    Chromatin structure and spatial interactions between proximal and distal gene regulatory elements, including gene core promoters and enhancers, are important in the control of gene transcription. In this issue, Oh et al. characterized an AP-1-dependent enhancer at the epidermal differentiation complex locus that establishes spatial interactions with numerous gene promoter regions at that locus.
    URI
    http://hdl.handle.net/10454/6831
    Version
    No full-text available in the repository
    Citation
    Fessing, M. Y. (2014) Gene regulation at a distance: higher-order chromatin folding and the coordinated control of gene transcription at the epidermal differentiation complex locus. Journal of Investigative Dermatology, 134 (9) 2307-10
    Link to publisher’s version
    http://dx.doi.org/10.1038/jid.2014.247
    Type
    Article
    Collections
    Life Sciences Publications

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