A safe, convenient and efficient method for the preparation of heterocyclic N-oxides using urea-hydrogen peroxide
| dc.contributor.author | Rong, Dawen | * |
| dc.contributor.author | Phillips, Victoria A. | * |
| dc.contributor.author | Rubio, R.S. | * |
| dc.contributor.author | Angeles Castro, M. | * |
| dc.contributor.author | Wheelhouse, Richard T. | * |
| dc.date.accessioned | 2014-04-28T11:18:22Z | |
| dc.date.available | 2014-04-28T11:18:22Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Rong, D., Phillips, Victoria A., Rubio, Ramon Sanchez, Angeles Castro, Ma, Wheelhouse, Richard T. (2008) A safe, convenient and efficient method for the preparation of heterocyclic N-oxides using urea-hydrogen peroxide. Tetrahedron Letters, 49 (48), 6933-6935. | |
| dc.identifier.uri | http://hdl.handle.net/10454/6160 | |
| dc.description.abstract | A novel, convenient, and high-yielding method has been developed for the preparation of heterocyclic N-oxides. The reaction uses the urea·hydrogen peroxide addition complex as a peroxide source for the in situ generation of trifluoroperacetic acid. The advantages of this method are easy handling of a stable, solid oxidant; high yields and simple removal of excess reagents and by-products. | en |
| dc.relation.isreferencedby | http://dx.doi.org/10.1016/j.tetlet.2008.09.124 | |
| dc.subject | REF 2014; N-Oxide; Urea·hydrogen peroxide; Trifluoroperacetic acid; Pyrimidine; Pyridine; Quinoline | |
| dc.title | A safe, convenient and efficient method for the preparation of heterocyclic N-oxides using urea-hydrogen peroxide | |
| dc.type | Article |