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dc.contributor.authorGrant, Colin A.*
dc.contributor.authorMcKendry, J.E.*
dc.contributor.authorEvans, S.D.*
dc.date.accessioned2012-12-04T15:41:07Z
dc.date.available2012-12-04T15:41:07Z
dc.date.issued03/11/2011
dc.identifier.citationGrant, C. A., McKendry, J. E. and Evans, S. D. (2012). Temperature dependent stiffness and visco-elastic behaviour of lipid coated microbubbles using atomic force microscopy. Soft Matter, Vol. 8, No. 5, pp. 1321-1326.en_US
dc.identifier.urihttp://hdl.handle.net/10454/5491
dc.descriptionyesen_US
dc.description.abstractThe compression stiffness of a phospholipid microbubble was determined using force-spectroscopy as a function of temperature. The stiffness was found to decrease by approximately a factor of three from 0.08 N m 1, at 10 C, down to 0.03 N m 1 at 37 C. This temperature dependence indicates that the surface tension of lipid coating is the dominant contribution to the microbubble stiffness. The timedependent material properties, e.g. creep, increased non-linearly with temperature, showing a factor of two increase in creep-displacement, from 24 nm, at 10 C, to 50 nm, at 37 C. The standard linear solid model was used to extract the visco-elastic parameters and their determination at different temperatures allowed the first determination of the activation energy for creep, for a microbubble, to be determined.en_US
dc.description.sponsorshipEPSRCen_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://pubs.rsc.org/en/Content/ArticleLanding/2012/SM/c1sm06578een_US
dc.rights© 2012 RSC Publishing. Reproduced in accordance with the publisher's self-archiving policy. Archived 12 months after accepted by date: Accepted 30th September 2011en_US
dc.subjectAtomic force micrscopyen_US
dc.subjectMicrobubbleen_US
dc.subjectNano-mechanicsen_US
dc.subjectCreepen_US
dc.subjectViscoelasticityen_US
dc.titleTemperature dependent stiffness and visco-elastic behaviour of lipid coated microbubbles using atomic force microscopy.en_US
dc.status.refereedYesen_US
dc.typeArticleen_US
dc.type.versionpublished version paperen_US
refterms.dateFOA2018-07-19T11:44:35Z


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