Temperature dependent stiffness and visco-elastic behaviour of lipid coated microbubbles using atomic force microscopy.
View/ Open
Soft_Matter2012_cover.pdf (1.235Mb)
Download
Publication date
03/11/2011Rights
© 2012 RSC Publishing. Reproduced in accordance with the publisher's self-archiving policy. Archived 12 months after accepted by date: Accepted 30th September 2011Peer-Reviewed
Yes
Metadata
Show full item recordAbstract
The compression stiffness of a phospholipid microbubble was determined using force-spectroscopy as a function of temperature. The stiffness was found to decrease by approximately a factor of three from 0.08 N m 1, at 10 C, down to 0.03 N m 1 at 37 C. This temperature dependence indicates that the surface tension of lipid coating is the dominant contribution to the microbubble stiffness. The timedependent material properties, e.g. creep, increased non-linearly with temperature, showing a factor of two increase in creep-displacement, from 24 nm, at 10 C, to 50 nm, at 37 C. The standard linear solid model was used to extract the visco-elastic parameters and their determination at different temperatures allowed the first determination of the activation energy for creep, for a microbubble, to be determined.Version
published version paperCitation
Grant, C. A., McKendry, J. E. and Evans, S. D. (2012). Temperature dependent stiffness and visco-elastic behaviour of lipid coated microbubbles using atomic force microscopy. Soft Matter, Vol. 8, No. 5, pp. 1321-1326.Link to Version of Record
https://doi.org/10.1039/C1SM06578EType
Articleae974a485f413a2113503eed53cd6c53
https://doi.org/10.1039/C1SM06578E