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    Refractive error, ocular biometry and oculomotor function: The prevalence of myopia and its potential risk factors in the Middle East, with an investigation of dynamic accommodation responses and axial length fluctuations in young myopic adults.

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    Yazan Gammoh, PhD.pdf (3.046Mb)
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    Publication date
    2012-02-10
    Author
    Gammoh, Yazan S.S.
    Supervisor
    Mallen, Edward A.H.
    Barrett, Brendan T.
    Douthwaite, William A.
    Keyword
    Refractive error
    Ocular biometry
    Occupational vision
    Oculomotor function
    Middle Eastern adults
    Young myopic adults
    Myopia
    Prevalence
    Rights
    Creative Commons License
    The University of Bradford theses are licenced under a Creative Commons Licence.
    Institution
    University of Bradford
    Department
    Optometry and Vision Science, Bradford School of Life Sciences,
    Awarded
    2011
    
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    Abstract
    The main experimental work of this thesis has been a cross-sectional study of the prevalence of refractive error and its biometric correlates in Middle Eastern adults. In addition dynamic accommodative responses and twenty-four hour axial length fluctuations were investigated in young myopic adults. The prevalence of myopia in 3000 Middle Eastern adults (age range 17-40 years) was similar to previously reported levels of myopia in the West. Myopia was associated with a higher level of education, occupations with a high nearwork demand and positive family history of myopia; all of which have been identified as risk factors for myopia development and progression Diurnal variations in axial length (AL) of similar magnitude to those previously reported in emmetropes were observed in myopes recruited in the current thesis. However, the pattern of the diurnal variation in AL was significantly different between early-onset myopes (EOMs) and late-onset myopes (LOMs). There were no significant differences between EOMs and LOMs in the dynamic accommodative response to a sinusoidally oscillating target. The accommodative phase lag was increased following 30 minute adaptation to myopic defocus using +2.00 D lens. However, intense prolonged (30 minute) nearwork was found to have no effect on accommodative gain or phase lag. A number of recommendations for further work on the prevalence of refractive error in the Middle East are suggested along with further research on diurnal AL variations and dynamic accommodative responses in EOMs and LOMs.
    URI
    http://hdl.handle.net/10454/5376
    Type
    Thesis
    Qualification name
    PhD
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    Theses

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