Synthesis of citrate-ciprofloxacin conjugates.
dc.contributor.author | Md-Saleh, S.R. | * |
dc.contributor.author | Chilvers, E.C. | * |
dc.contributor.author | Kerr, Kevin G. | * |
dc.contributor.author | Milner, S.J. | * |
dc.contributor.author | Snelling, Anna M. | * |
dc.contributor.author | Weber, J.P. | * |
dc.contributor.author | Thomas, G.H. | * |
dc.contributor.author | Duhme-Klair, A-K. | * |
dc.contributor.author | Routledge, A. | * |
dc.date.accessioned | 2011-03-14T14:41:37Z | |
dc.date.available | 2011-03-14T14:41:37Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Md-Saleh, S. R., Chilvers, E. C., Kerr, K. G., Milner, S. J., Snelling, A. M., Weber, J. P., Thomas, G. H., Duhme-Klair, A-K. and Routledge, A. (2009). Synthesis of citrate-ciprofloxacin conjugates. Bioorganic & Medicinal Chemistry Letters. Vol. 19, pp. 1496-1498. | en_US |
dc.identifier.uri | http://hdl.handle.net/10454/4843 | |
dc.description | no | en_US |
dc.description.abstract | Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12. | en_US |
dc.language.iso | en | en_US |
dc.subject | Citrate-ciprofloxacin conjugates | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Antibiotics | en_US |
dc.subject | Ciprofloxacin | en_US |
dc.subject | Synthesis | en_US |
dc.title | Synthesis of citrate-ciprofloxacin conjugates. | en_US |
dc.status.refereed | Yes | en_US |
dc.type | Article | en_US |
dc.type.version | published version paper | en_US |
dc.identifier.doi | https://doi.org/10.1016/j.bmcl.2009.01.007 |