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    Synthesis of citrate-ciprofloxacin conjugates.

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    Publication date
    2009
    Author
    Md-Saleh, S.R.
    Chilvers, E.C.
    Kerr, Kevin G.
    Milner, S.J.
    Snelling, Anna M.
    Weber, J.P.
    Thomas, G.H.
    Duhme-Klair, A-K.
    Routledge, A.
    Keyword
    Citrate-ciprofloxacin conjugates
    Antimicrobial activity
    Antibiotics
    Ciprofloxacin
    Synthesis
    Peer-Reviewed
    Yes
    
    Metadata
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    Abstract
    Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12.
    URI
    http://hdl.handle.net/10454/4843
    Version
    published version paper
    Citation
    Md-Saleh, S. R., Chilvers, E. C., Kerr, K. G., Milner, S. J., Snelling, A. M., Weber, J. P., Thomas, G. H., Duhme-Klair, A-K. and Routledge, A. (2009). Synthesis of citrate-ciprofloxacin conjugates. Bioorganic & Medicinal Chemistry Letters. Vol. 19, pp. 1496-1498.
    Link to publisher’s version
    https://doi.org/10.1016/j.bmcl.2009.01.007
    Type
    Article
    Collections
    Life Sciences Publications

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