Vibrational spectroscopic study of fluticasone propionate
dc.contributor.author | Ali, H.R.H. | * |
dc.contributor.author | Edwards, Howell G.M. | * |
dc.contributor.author | Kendrick, John | * |
dc.contributor.author | Scowen, Ian J. | * |
dc.date.accessioned | 2011-01-20T11:14:50Z | |
dc.date.available | 2011-01-20T11:14:50Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Ali HRH, Edwards HGM, Kendrick J and Scowen IJ (2009) Vibrational spectroscopic study of fluticasone propionate. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 72(2): 244-247. | en |
dc.identifier.uri | http://hdl.handle.net/10454/4724 | |
dc.description | No | en |
dc.description.abstract | Luticasone propionate is a synthetic glucocorticoid with potent anti-inflammatory activity that has been used effectively in the treatment of chronic asthma. The present work reports a vibrational spectroscopic study of fluticasone propionate and gives proposed molecular assignments on the basis of ab initio calculations using BLYP density functional theory with a 6-31G* basis set and vibrational frequencies predicted within the quasi-harmonic approximation. Several spectral features and band intensities are explained. This study generated a library of information that can be employed to aid the process monitoring of fluticasone propionate. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.relation.isreferencedby | http://dx.doi.org/10.1016/j.saa.2008.08.004 | en |
dc.subject | Raman Spectroscopy | en |
dc.subject | ; Infrared spectroscopy | en |
dc.subject | ; Fluticasone propionate | en |
dc.subject | ; Respiratory pharmaceuticals | en |
dc.subject | ; Ab initio structural calculations | en |
dc.title | Vibrational spectroscopic study of fluticasone propionate | en |
dc.status.refereed | Yes | en |
dc.type | Article | en |
dc.type.version | No full-text available in the repository | en |