An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide
| dc.contributor.author | Ali, H.R.H. | * |
| dc.contributor.author | Edwards, Howell G.M. | * |
| dc.contributor.author | Kendrick, John | * |
| dc.contributor.author | Munshi, Tasnim | * |
| dc.contributor.author | Scowen, Ian J. | * |
| dc.date.accessioned | 2010-12-21T16:56:42Z | |
| dc.date.available | 2010-12-21T16:56:42Z | |
| dc.date.issued | 2010 | |
| dc.identifier.citation | Ali, H.R.H., Edwards, H.G.M., Kendrick, J., Munshi, T. and Scowen, I.J. (2010). An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide. Drug Testing and Analysis. Vol. 2, No. 9, pp. 447¿451. | |
| dc.identifier.uri | http://hdl.handle.net/10454/4620 | |
| dc.description | No | |
| dc.description.abstract | Budesonide is a mixture of 22R and 22S epimers. The epimeric content of budesonide was reported in both British and European pharmacopoeias to be within the range of 60-49/40-51 for R and S epimers, respectively. In this work, contribution of the two epimers to the overall infrared spectrum of budesonide has been investigated by quantum chemical calculations. | |
| dc.language.iso | en | |
| dc.subject | Budesonide | |
| dc.subject | Epimers | |
| dc.subject | Infrared | |
| dc.subject | Pharmaceuticals | |
| dc.subject | Quantum mechanics | |
| dc.subject | Quantum chemical calculations | |
| dc.title | An experimental and computational study on the epimeric contribution to the infrared spectrum of budesonide | |
| dc.status.refereed | Yes | |
| dc.type | Article | |
| dc.type.version | No full-text in the repository | |
| dc.identifier.doi | https://doi.org/10.1002/dta.152 | |
| dc.openaccess.status | closedAccess |