BRADFORD SCHOLARS

    • Sign in
    View Item 
    •   Bradford Scholars
    • Life Sciences
    • Life Sciences Publications
    • View Item
    •   Bradford Scholars
    • Life Sciences
    • Life Sciences Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Bradford ScholarsCommunitiesAuthorsTitlesSubjectsPublication DateThis CollectionAuthorsTitlesSubjectsPublication Date

    My Account

    Sign in

    HELP

    Bradford Scholars FAQsCopyright Fact SheetPolicies Fact SheetDeposit Terms and ConditionsDigital Preservation Policy

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley and Dendly).

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Publication date
    2010
    Author
    Rao, T.S.P.
    Sarma, N.S.
    Murthy, Y.L.N.
    Kantamreddi, Venkata Siva Satya Narayana
    Wright, Colin W.
    Parameswaran, P.S.
    Keyword
    Marine natural products
    Antiplasmodial
    Polyhydroxy sterols
    Callyspongia fibrosa
    Peer-Reviewed
    Yes
    
    Metadata
    Show full item record
    Abstract
    Four new polyhydroxylated sterols are isolated from Marine sponge Callyspongia fibrosa collected from the Gulf of Mannar, western Bay of Bengal (India). The structural assignment is based on 1H and 13C NMR spectra. All sterols are based on the known 24S-24-methyl cholesterol 1 which is also isolated, and contain 3b,6b-dihydroxy system and 25-O-acetate as common features (except in the case of sterol 6 that has a D25 in the place of 25-OAc). Additional OH substitution is also present at 5a in 4a and at 8b in 5. A further 12b-OH is present in 6 and 7. The hydroxylation pattern is so far known only in coral sterols but is without a precedent in sponge sterols. The major steroid 4a showed antimalarial activity against Plasmodium falciparum on the chloroquine-resistant stain better than on the chloroquine-sensitive strain.
    URI
    http://hdl.handle.net/10454/4540
    Version
    No full-text available in the repository
    Citation
    Rao, T. S. P., Sarma, N. S., Murthy, Y. L. N., Kantamreddi V. S. S. N., Wright, C. W. and Parameswaran, P. S. (2010). New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley and Dendly). Tetrahedron Letters, Vol. 51, No. 27, pp. 3583-3586.
    Link to publisher’s version
    http://dx.doi.org/doi:10.1016/j.tetlet.2010.05.009
    Type
    Article
    Collections
    Life Sciences Publications

    entitlement

     
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.