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Prenylated flavonoid derivatives from the bark of Erythrina addisoniae.

dc.contributor.authorWatjen, W.*
dc.contributor.authorSuckow-Schnitker, A-K.*
dc.contributor.authorRohrig, R.*
dc.contributor.authorKulawik, A.*
dc.contributor.authorAddae-Kyereme, Jonathan A.*
dc.contributor.authorWright, Colin W.*
dc.contributor.authorPassreiter, C.M.*
dc.date.accessioned2010-12-07T12:28:42Z
dc.date.available2010-12-07T12:28:42Z
dc.date.issued2008
dc.identifier.citationWätjen, W., Suckow-Schnitker, A. K., Rohrig, R., Kulawik, A., Addae-Kyereme, J., Wright, C. W. and C. M. Passreiter. (2008). Prenylated flavonoid derivatives from the bark of Erythrina addisoniae. Journal of Natural Products. Vol. 71, No. 4, pp. 735-738.en
dc.identifier.urihttp://hdl.handle.net/10454/4532
dc.descriptionnoen
dc.description.abstractTwo new prenylated flavanones, 2S-3¿-(2-hydroxy-3-methylbut-3-enyl)licoflavone-4¿-methyl ether (3) and 2S-3¿-(2- hydroxy-3-methylbut-3-enyl)abyssinone II (4), and four known flavanones (1, 2, 5, 6) were isolated from the stem bark of Erythrina addisoniae. The structures were elucidated on the basis of their spectroscopic and physicochemical data. None of the compounds showed antioxidative properties. 4¿-Methylabyssinone V (1) and abyssinoflavanone VII (6) showed moderate cytotoxic activity (IC50 ) 5 and 3.5 ¿mol/L, respectively), but apoptosis (caspase-3/7-activation, nuclear fragmentation) was selectively induced by abyssinoflavanone VII (6).en
dc.language.isoenen
dc.publisherAmerican Chemical Societyen
dc.relation.isreferencedbyhttp://dx.doi.org/10.1021/np070417jen
dc.subjectErythrinaen
dc.subjectPrenylated flavonoidsen
dc.titlePrenylated flavonoid derivatives from the bark of Erythrina addisoniae.en
dc.status.refereedYesen
dc.typeArticleen
dc.identifier.JournalTitleJournal of Natural Productsen
dc.type.versionpublished version paperen


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