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dc.contributor.authorAfarinkia, Kamyar*
dc.contributor.authorBahar, A.*
dc.contributor.authorBearpark, M.J.*
dc.contributor.authorGarcia-Ramos, J.*
dc.contributor.authorRuggiero, A.*
dc.contributor.authorNeuse, J.*
dc.contributor.authorVyas, M.*
dc.date.accessioned2009-10-26T14:14:06Z
dc.date.available2009-10-26T14:14:06Z
dc.date.issued2005
dc.identifier.citationAfarinkia, K., Bahar, A., Bearpark, M.J. and Garcia-Ramos, J et al. (2005). An Investigation of the Diels-Alder Cycloadditions of 2(H)-1,4-Oxazin-2-ones. Journal of Organic Chemistry. Vol. 70, No. 23, pp. 9529-9537.en
dc.identifier.urihttp://hdl.handle.net/10454/3750
dc.descriptionNoen
dc.description.abstractForumla chem. . A variety of 5-chloro-2(H)-1,4-oxazin-2-ones bearing a range of substituents at their 3- and 6-positions undergo Diels-Alder cycloaddition as a 2-azadiene component with electron-rich, electron-deficient, and electron-neutral dienophiles. These reactions proceed with moderate regio- and stereoselectivity to afford relatively stable and readily isolable bridged bicyclic lactone cycloadducts. Chemical manipulation of these cycloadducts affords highly substituted and functionally rich piperidines. The regio- and stereochemical preferences of the cycloadditions of 5-chloro-2(H)-1,4-oxazin-2-ones are investigated computationally using density functional theory (B3LYP/6-31G*).en
dc.language.isoenen
dc.relation.isreferencedbyhttp://dx.doi.org/10.1021/jo051646ien
dc.subjectOxygen nitrogen heterocycleen
dc.subjectNitrogen heterocycleen
dc.subjectOxygen heterocycleen
dc.subjectKetoneen
dc.subjectOxazine derivativesen
dc.subjectDensity functional methoden
dc.subjectStereochemistryen
dc.subjectPiperidine derivativesen
dc.subjectLactoneen
dc.subjectDiels Alder additionen
dc.subjectStereoselectivityen
dc.subjectRegioselectivityen
dc.titleAn Investigation of the Diels-Alder Cycloadditions of 2(H)-1,4-Oxazin-2-ones.en
dc.status.refereedYesen
dc.typeArticleen
dc.type.versionNo full-text available in the repositoryen


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