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dc.contributor.authorLewis, R.W.*
dc.contributor.authorGethin, D.T.*
dc.contributor.authorYang, X.S.*
dc.contributor.authorRowe, Raymond C.*
dc.date.accessioned2009-06-09T14:29:22Z
dc.date.available2009-06-09T14:29:22Z
dc.date.issued2009-06-09T14:29:22Z
dc.identifier.citationLewis, R.W., Gethin, D.T., Ysng, X.S. and Rowe, R.C. (2005) A combined finite-discrete element method for simulating pharmaceutical powder tableting. International Journal for Numerical Methods in Engineering. Vol. 62, No 7, pp. 853-869.en
dc.identifier.urihttp://hdl.handle.net/10454/2793
dc.descriptionNoen
dc.description.abstractThe pharmaceutical powder and tableting process is simulated using a combined finite-discrete element method and contact dynamics for irregular-shaped particles. The particle-scale formulation and two-stage contact detection algorithm which has been developed for the proposed method enhances the overall calculation efficiency for particle interaction characteristics. The irregular particle shapes and random sizes are represented as a pseudo-particle assembly having a scaled up geometry but based on the variations of real powder particles. Our simulations show that particle size, shapes and material properties have a significant influence on the behaviour of compaction and deformation.en
dc.language.isoenen
dc.relation.isreferencedbyhttp://www3.interscience.wiley.com/cgi-bin/fulltext/109876201/PDFSTARTen
dc.subjectDiscrete element methoden
dc.subjectElasticityen
dc.subjectViscoelasticityen
dc.subjectFinite element analysisen
dc.subjectPharmaceutical powderen
dc.subjectTabletingen
dc.titleA combined finite-discrete element method for simulating pharmaceutical powder tabletingen
dc.status.refereedYesen
dc.typeArticleen
dc.type.versionNo full-text available in the repositoryen


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