Routine omics collection is a golden opportunity for European human research in space and analog environments

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2022-10Author
Cope, H.Willis, Craig R.G.
MacKay, M.J.
Rutter, L.A.
Toh, L.S.
Williams, P.M.
Herranz, R.
Borg, J.
Bezdan, D.
Giacomello, S.
Muratani, M.
Mason, C.E.
Etheridge, T.
Szewczyk, N.J.
Keyword
MultiomicsEuropean Space Agency
Commercial spaceflight
Personalized medicine
International Space Station
Longitudinal monitoring
GDPR
Astronaut ethics
Biobank
Artificial intelligence
Rights
© 2022 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Peer-Reviewed
YesOpen Access status
openAccessAccepted for publication
2022
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Show full item recordAbstract
Widespread generation and analysis of omics data have revolutionized molecular medicine on Earth, yet its power to yield new mechanistic insights and improve occupational health during spaceflight is still to be fully realized in humans. Nevertheless, rapid technological advancements and ever-regular spaceflight programs mean that longitudinal, standardized, and cost-effective collection of human space omics data are firmly within reach. Here, we consider the practicality and scientific return of different sampling methods and omic types in the context of human spaceflight. We also appraise ethical and legal considerations pertinent to omics data derived from European astronauts and spaceflight participants (SFPs). Ultimately, we propose that a routine omics collection program in spaceflight and analog environments presents a golden opportunity. Unlocking this bright future of artificial intelligence (AI)-driven analyses and personalized medicine approaches will require further investigation into best practices, including policy design and standardization of omics data, metadata, and sampling methods.Version
Published versionCitation
Cope H, Willis CRG, MacKay MJ et al (2022) Routine omics collection is a golden opportunity for European human research in space and analog environments. Patterns. 3(10): 100550 .Link to Version of Record
https://doi.org/10.1016/j.patter.2022.100550Type
Articleae974a485f413a2113503eed53cd6c53
https://doi.org/10.1016/j.patter.2022.100550