Concordance of objectively-detected retinal nerve fiber bundle defects in en face OCT images with conventional structural and functional changes in glaucoma.

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Publication date
2023-01
Author
Cheloni, Riccardo
Denniss, Jonathan
Keyword
En face OCT
Glaucoma
OCT
Retinal nerve fiber layer
Reflectance
Rights
(c) 2023 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license (https://creativecommons.org/licenses/by/4.0/)
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Yes
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openAccess

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Abstract
To assess how objectively-detected defects of retinal nerve fibre bundle (RNFB) reflectance in en face OCT images relate to circumpapillary retinal nerve fibre layer thickness (cpRNFLT) and visual field defects. Cross-sectional study. 16 participants with early-glaucoma and 29 age-similar healthy controls, among which 22 had usable en face images to establish normative levels of RNFB reflectance. All participants underwent cpRNFLT scans, visual field examination and wide-field OCT. En face reflectivity was assessed objectively using the Summary of Multiple Anatomically-Adjusted Slabs (SMAS) method. En face defects were deemed concordant with cpRNFLT when they had at least one cpRNFLT point with p
URI
http://hdl.handle.net/10454/19151
Version
Published version
Citation
Cheloni R and Dennis J (2023) Concordance of objectively-detected retinal nerve fiber bundle defects in en face OCT images with conventional structural and functional changes in glaucoma. Ophthalmology Glaucoma. 6(1): 78-92.
Link to publisher’s version
https://doi.org/10.1016/j.ogla.2022.07.001
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Article
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