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dc.contributor.authorMaleki, A.
dc.contributor.authorGhomi, M.
dc.contributor.authorNikfarjam, N.
dc.contributor.authorAkbari, M.
dc.contributor.authorSharifi, E.
dc.contributor.authorShahbazi, M-A.
dc.contributor.authorKermanian, M.
dc.contributor.authorSeyedhamzeh, M.
dc.contributor.authorZare, E.N.
dc.contributor.authorMehrali, M.
dc.contributor.authorMoradi, O.
dc.contributor.authorSefat, Farshid
dc.contributor.authorMattoli, V.
dc.contributor.authorMakvandi, P.
dc.contributor.authorChen, Y.
dc.date.accessioned2022-07-07T10:25:16Z
dc.date.accessioned2022-07-08T14:42:09Z
dc.date.available2022-07-07T10:25:16Z
dc.date.available2022-07-08T14:42:09Z
dc.date.issued2022-08
dc.identifier.citationMaleki A, Ghomi M, Nikfarjam N et al (2022) Biomedical applications of MXene-integrated composites: regenerative medicine, infection therapy, cancer treatment, and biosensing. Advanced Functional Materials. 32(34): 2203430.en_US
dc.identifier.urihttp://hdl.handle.net/10454/19055
dc.descriptionYesen_US
dc.description.abstractMXenes (viz., transition metal carbides, carbonitrides, and nitrides) have emerged as a new subclass of 2D materials. Due to their outstanding physicochemical and biological properties, MXenes have gained much attention in the biomedical field in recent years, including drug delivery systems, regenerative medicine, and biosensing. Additionally, the incorporation of MXenes into hydrogels has garnered significant interest in biomedical engineering as an electroactive and mechanical nanoreinforcer capable of converting nonconductive scaffolds into excellent conductors of electricity with an impressive effect on mechanical properties for the engineering of electroactive organs and tissues such as cardiac, skeletal muscle, and nerve. However, many questions and problems remain unresolved that need to be answered to usher these 2D materials toward their true destiny. Thus, this review paper aims to provide an overview of the design and applications of MXene-integrated composites for biomedical applications, including cardiac tissue engineering, wound healing, infection therapy, cancer therapy, and biosensors. Moreover, the current challenges and limitations of utilizing MXenes in vivo are highlighted and discussed, followed by its prospects as a guideline toward possible various futuristic biomedical applications. This review article will inspire researchers, who search for properties, opportunities, and challenges of using this 2D nanomaterial in biomedical applications.en_US
dc.description.sponsorshipOpen Access Funding provided by Istituto Italiano di Tecnologia within the CRUI-CARE Agreement.en_US
dc.language.isoenen_US
dc.publisherWiley-VCH GmbH
dc.rights© 2022 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en_US
dc.subject2D materialsen_US
dc.subjectBiological propertiesen_US
dc.subjectBiomedical applicationsen_US
dc.subjectIntegrated compositesen_US
dc.subjectMXenesen_US
dc.titleBiomedical applications of MXene-integrated composites: regenerative medicine, infection therapy, cancer treatment, and biosensingen_US
dc.status.refereedYesen_US
dc.date.Accepted2022-05
dc.date.application2022-06-24
dc.typeArticleen_US
dc.type.versionPublished versionen_US
dc.identifier.doihttps://doi.org/10.1002/adfm.202203430
dc.rights.licenseCC-BYen_US
dc.date.updated2022-07-07T10:25:20Z
refterms.dateFOA2022-07-08T14:42:57Z
dc.openaccess.statusopenAccessen_US


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