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    Biomaterials for breast reconstruction: Promises, advances, and challenges

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    Publication date
    2020-11
    Author
    Abdul-Al, Mohamed
    Zaernia, Amir
    Sefat, Farshid
    Keyword
    Biomaterials
    Breast
    Mastectomy
    Reconstruction
    Regenerative medicine
    Scaffold
    Rights
    © 2020 The Authors. Journal of Tissue Engineering and Regenerative Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
    Peer-Reviewed
    yes
    Open Access status
    Gold
    
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    Abstract
    Breast reconstruction is the opportunity that provides the chance of having breast after undergoing surgical removal of the breast tissue due to cancer-related surgery. However, this varies on the stage of the cancer diagnosis and the procedure undertaken. There are many regenerative medicine methods that provide several initiatives and direct solutions to problems such as the development of “bioactive tissue,” which can regenerate adipose tissues with similar normal functions and structures. There have been several studies which have previously explored for the improvement of breast reconstruction including different variations of biomaterials, different fabrication and processing techniques, cells as well as growth factors which enable bioengineers and tissue engineers to reconstruct a suitable breast for patients with breast cancer. Many factors such as shape, proper volume, mechanical properties have been studies but very scattered with not adequate solutions for existing patients worldwide. This review article aims to cover recent advances in biomaterials, which can be used for reconstruction of breasts as well as looking at the various factors that might lead to individuals needing reconstruction and the materials that are available. The focus would be to look at the various biomaterials that are available to use for reconstruction, their properties, and their structural integrity.
    URI
    http://hdl.handle.net/10454/18691
    Version
    Published version
    Citation
    Abdul-Al M, Zaernia A and Sefat, F. (2020) Biomaterials for breast reconstruction: Promises, advances, and challenges. Journal of Tissue Engineering and Regenerative Medicine. 14(11): 1549–1569.
    Link to publisher’s version
    https://doi.org/10.1002/term.3121
    Type
    Article
    Collections
    Engineering and Informatics Publications

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