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    Fast versus gradual adaptation of soft monthly contact lenses in neophyte wearers

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    wolffson_et_al_2021.pdf (268.2Kb)
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    Publication date
    2022-08-01
    Author
    Wolffsohn, J.S.
    Ghorbani Mojarrad, Neema
    Vianya-Estopa, M.
    Nagra, M.
    Huntjens, B.
    Terry, L.
    Sweeney, L.E.
    Dutta, D.
    Joshi, M.R.
    Wright, D.
    Bruce, H.
    Hallam, E.
    Jolly, L.
    Chung, Y.B.
    Tsen, J.R.E.
    Bishop, A.
    Davison, R.
    Maldonado-Codina, C.
    Show allShow less
    Keyword
    Soft contact lens
    Reusable
    Adaptation
    Neophyte
    Fast
    Gradual
    Rights
    © 2022 Elsevier. Reproduced in accordance with the publisher's self-archiving policy. This manuscript version is made available under the CC-BY-NC-ND 4.0 license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
    Peer-Reviewed
    Yes
    Open Access status
    openAccess
    
    Metadata
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    Abstract
    To determine if a gradual adaptation period is necessary for neophytes when fitted with modern hydrogel or silicone hydrogel reusable disposable contact lenses. Across four sites, 74 neophytes (18-28 years) were randomly assigned to a reusable lens cleaned nightly with Opti-Free® Puremoist® multi-purpose contact lens solution: Proclear® (hydrogel) or Biofinity® (silicone hydrogel) and an adaptation schedule: fast (10 h wear from the first day) or gradual (4 h on the first day, increasing their wear time by 2 h on each subsequent day until they had reached 10 h). Masked investigators graded ocular surface physiology and non-invasive tear breakup time (NIBUT) and a range of comfort, vision and lens handling subjective ratings (0-100 visual analogue scales) were recorded at the baseline visit and after 10 h of lens wear, 4-6 days and 12-14 days after lens fitting. Subjective scores were also repeated after 7 days. There was no difference (p > 0.05) in ocular surface physiology or NIBUT between fast and gradual adaptation groups at any time point in either lens type with the exception of increased corneal staining (p = 0.019) in the silicone hydrogel fast adaptation group after 4-6 days, but was similar by 12-14 days. Subjective scores were also similar across the visits and lens types with the exception of 'lens awareness' (p = 0.019) which was less in the gradual versus the fast adaptation silicone hydrogel lens group at 12-14 days. There seems to be no clinical benefit for recommending a gradual adaptation period in new wearers fitted with modern soft reusable disposable contact lenses. The findings of this work add to a growing body of evidence suggesting that such advice is unnecessary in regular soft contact lens wear, which has important ramifications for the initial clinical management of these patients.
    URI
    http://hdl.handle.net/10454/18649
    Version
    Accepted manuscript
    Citation
    Wolffsohn JS, Ghorbani Mojarrad N, Vianya-Estopa M et al (2022) Fast versus gradual adaptation of soft monthly contact lenses in neophyte wearers. Contact Lens and Anterior Eye. 45(4): 101469.
    Link to publisher’s version
    https://doi.org/10.1016/j.clae.2021.101469
    Type
    Article
    Collections
    Life Sciences Publications

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