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dc.contributor.authorRubinstein, N.J.
dc.contributor.authorTurpin, A.
dc.contributor.authorDenniss, Jonathan
dc.contributor.authorMcKendrick, A.M.
dc.date.accessioned2021-02-15T10:38:01Z
dc.date.accessioned2021-02-17T15:18:55Z
dc.date.available2021-02-15T10:38:01Z
dc.date.available2021-02-17T15:18:55Z
dc.date.issued2021-01
dc.identifier.citationRubinstein NJ, Turpin A, Denniss J et al (2021) Effects of criterion bias on perimetric sensitivity and response variability in glaucoma. Translational Vision Science & Technology. 10(1): Article 18.en_US
dc.identifier.urihttp://hdl.handle.net/10454/18349
dc.descriptionYesen_US
dc.description.abstractThe purpose of this study was to isolate and quantify the effects of observer response criterion on perimetric sensitivity, response variability, and maximum response probability. Twelve people with glaucoma were tested at three locations in the visual field (age = 47-77 years, mean deviation = -0.61 to -14.54 dB, test location Humphrey field analyzer [HFA] sensitivities = 1 to 30 dB). Frequency of seeing (FoS) curves were measured using a method of constant stimuli with two response paradigms: a "yes-no" paradigm similar to static automated perimetry and a criterion-free two interval forced choice (2IFC) paradigm. Comparison measures of sensitivity, maximum response probability, and response variability were derived from the fitted FoS curves. Sensitivity differences between the tasks varied widely (range = -11.3 dB to 21.6 dB) and did not correlate with visual field sensitivity nor whether the visual field location was in an area of steep sensitivity gradient within the visual field. Due to the wide variation in differences between the methods, there was no significant difference in mean sensitivity between the 2IFC task relative to the yes-no task, but a trend for higher sensitivity (mean = 1.9 dB, SD = 6.0 dB, P = 0.11). Response variability and maximum response probability did not differ between the tasks (P > 0.99 and 0.95, respectively). Perimetric sensitivity estimates are demonstrably altered by observer response criterion but the effect varies widely and unpredictably, even within a single test. Response bias should be considered a factor in perimetric test variability and when comparing sensitivities to nonperimetric data. The effect of response criterion on perimetric response variability varies widely and unpredictably, even within a single test.en_US
dc.description.sponsorshipSupported by ARC LP130100055; ARC LP150100815 (AT and AMM), College of Optometrists Research Fellowship (JD).en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttps://doi.org/10.1167/tvst.10.1.18en_US
dc.rightsCopyright 2021 The Authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.subjectPerimetryen_US
dc.subjectVisual fielden_US
dc.subjectGlaucomaen_US
dc.subjectCriterionen_US
dc.subjectVariabilityen_US
dc.subjectBiasen_US
dc.titleEffects of criterion bias on perimetric sensitivity and response variability in glaucomaen_US
dc.status.refereedYesen_US
dc.date.Accepted2020-11-04
dc.date.application2021-01-08
dc.typeArticleen_US
dc.type.versionPublished versionen_US
dc.date.updated2021-02-15T10:38:02Z
refterms.dateFOA2021-02-18T09:29:14Z
dc.openaccess.statusGreenen_US


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