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Investigation of cytochrome p450 isoforms 1A1, 1B1 and 2W1 as targets for therapeutic intervention in head and neck cancer. Probing CYP1A1, 1B1 and 2W1 activity with duocarmycin bioprecursors

dc.contributor.advisorPatterson, Laurence H.
dc.contributor.advisorMcCaul, Jim
dc.contributor.advisorPors, Klaus
dc.contributor.authorPresa, Daniela
dc.date.accessioned2020-11-18T12:15:18Z
dc.date.available2020-11-18T12:15:18Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/10454/18171
dc.language.isoenen_US
dc.rights<a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><img alt="Creative Commons License" style="border-width:0" src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" /></a><br />The University of Bradford theses are licenced under a <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/">Creative Commons Licence</a>.en_US
dc.subjectCytochrome P450 (CYP)en_US
dc.subjectCYP1A1en_US
dc.subjectCYP1B1en_US
dc.subjectCYP2W1en_US
dc.subjectHead and Neck Cancer (HNC)en_US
dc.subjectDuocarmycinen_US
dc.subjectProdrugen_US
dc.subjectBioprecursoren_US
dc.subjectDNA damageen_US
dc.subjectTherapeutic interventionen_US
dc.titleInvestigation of cytochrome p450 isoforms 1A1, 1B1 and 2W1 as targets for therapeutic intervention in head and neck cancer. Probing CYP1A1, 1B1 and 2W1 activity with duocarmycin bioprecursorsen
dc.type.qualificationleveldoctoralen_US
dc.publisher.institutionUniversity of Bradfordeng
dc.publisher.departmentInstitute of Cancer Therapeutics, Faculty of Life Sciencesen_US
dc.typeThesiseng
dc.type.qualificationnamePhDen_US
dc.date.awarded2018
dc.description.publicnotesThe full text will be available at the end of the embargo: 30th July 2026en
refterms.dateFOA2020-11-18T12:15:19Z
dc.date.endofembargo2026-07-30


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