Highly branched poly(N-isopropyl acrylamide) functionalized with an inducer molecule suppresses quorum sensing in Chromobacterium violaceum
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2019-07Rights
(c) 2019 The Authors. This is an Open Access article distributed under the Creative Commons CC-BY license.Peer-Reviewed
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Bacterial quorum sensing has been implicated in a number of pathogenic bacterial processes, such as biofilm formation, making it a crucial target for developing materials with a novel antibiotic mode of action. This paper describes poly(N-isopropyl acrylamide) that has been covalently linked, at multiple chain ends, to homoserine lactone to give a highly branched polymer functionalized with a key messenger molecule implicated in QS. This novel functional material has shown promising anti-QS activity in a Chromobacterium violaceum assay.Version
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Shepherd J, Swift T, Chang C-Y, Boyne JR, Rimmer S and Martin WHC (2019) Highly branched poly(N-isopropyl acrylamide) functionalized with an inducer molecule suppresses quorum sensing in Chromobacterium violaceum. Chemical Communications. 55(66): 9765-9768.Link to Version of Record
https://doi.org/10.1039/C9CC02524CType
Articleae974a485f413a2113503eed53cd6c53
https://doi.org/10.1039/C9CC02524C