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    Antibacterial glass-ionomer cement restorative materials: A critical review on the current status of extended release formulations

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    Publication date
    2017-09-28
    Author
    Hafshejani, T.M.
    Zamanian, A.
    Venugopal, J.R.
    Rezvani, Z.
    Sefat, Farshid
    Saeb, M.R.
    Vahabi, H.
    Zarrintaj, P.
    Mozafari, M.
    Keyword
    Glass ionomer cement
    Antibacterial
    Controlled release
    Caries
    Peer-Reviewed
    Yes
    
    Metadata
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    Abstract
    Glass-ionomer cements (GICs) have been widely used for over forty years, because of their desirable properties in dentistry. The most important advantages of the GICs are associated with their ability to release long-term antimicrobial agents. However, GICs used as restorative materials have still lots of challenges due to their secondary caries and low mechanical properties. Recent studies showed that the fluoride-releasing activity of conventional GICs is inadequate for effectual antibacterial conservation in many cases. Therefore, many efforts have been proposed to modify the antibacterial features of GICs in order to prevent the secondary caries. Particularly, for achieving this goal GICs were incorporated into various biomaterials possessing antibacterial activities. The scope of this review is to assess systematically the extant researches addressing the antibacterial modifications in GICs in order to provide with an authoritative, at the same time in-depth understanding of controlled antibacterial release in this class of biomaterials. It also gives a whole perspective on the future developments of GICs and challenges related to antibacterial GICs.
    URI
    http://hdl.handle.net/10454/16997
    Version
    No full-text in the repository
    Citation
    Hafshejani TM, Zamanian A, Venugopal JR (2017) Antibacterial glass-ionomer cement restorative materials: A critical review on the current status of extended release formulations. Journal of Controlled Release. 262: 317-328.
    Link to publisher’s version
    https://doi.org/10.1016/j.jconrel.2017.07.041
    Type
    Article
    Collections
    Engineering and Informatics Publications

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