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dc.contributor.authorZolfigol, M.A.*
dc.contributor.authorKhazaei, A.*
dc.contributor.authorKarimitabar, F.*
dc.contributor.authorHamidi, M.*
dc.contributor.authorMaleki, F.*
dc.contributor.authorAghabarari, B.*
dc.contributor.authorSefat, Farshid*
dc.contributor.authorMozafari, M.*
dc.date.accessioned2019-04-29T15:51:54Z
dc.date.available2019-04-29T15:51:54Z
dc.date.issued2018-04
dc.identifier.citationZolfigol MA, Khazaei A, Karimitabar F et al (2018) Synthesis of Indolo[3,2-b]carbazoles via an Anomeric-Based Oxidation Process: A Combined Experimental and Computational Strategy. Journal of Heterocyclic Chemistry. 55(4): 1061-1068.en_US
dc.identifier.urihttp://hdl.handle.net/10454/16993
dc.descriptionNoen_US
dc.description.abstractIndolo[3,2-b]carbazole is a molecule of great biological significance, as it is formed in vivo after consumption of cruciferous vegetables. The reaction of 1H-indole and various aldehydes in the presence of a catalytic amount of N,2-dibromo-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide as an efficient and homogeneous catalyst in acetonitrile at 50°C produces 6,12-disubstituted 5,7-dihydroindolo[2,3-b]carbazole with an in good to excellent yield. The presented technique offers a fast and robust method, by the use of inexpensive commercially available starting materials toward 6,12- disubstituted 5,7-dihydroindolo[2,3-b]carbazole. A new anomeric-based oxidation was kept in mind for the final step of the indolo[2,3-b]carbazoles synthesis. The suggested anomeric-based oxidation mechanism was supported by experimental and theoretical evidences.en_US
dc.description.sponsorshipThe Grant of Allameh Tabataba’i’s Award, Grant Number: BN093en_US
dc.language.isoenen_US
dc.subjectIndolo[3,2-b]carbazolesen_US
dc.subjectSynthesisen_US
dc.subjectAnomeric-Based Oxidationen_US
dc.titleSynthesis of Indolo[3,2-b]carbazoles via an Anomeric-Based Oxidation Process: A Combined Experimental and Computational Strategyen_US
dc.status.refereedYesen_US
dc.date.Accepted2017-12-03
dc.date.application2018-02-01
dc.typeArticleen_US
dc.type.versionNo full-text in the repositoryen_US
dc.identifier.doihttps://doi.org/10.1002/jhet.3077
refterms.dateFOA2019-04-29T15:51:54Z


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