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dc.contributor.authorKaur, Payal*
dc.contributor.authorKhaghani, Seyed A.*
dc.contributor.authorOluwadamilola, Agbabiaka*
dc.contributor.authorKhurshid, Z.*
dc.contributor.authorZafar, M.S.*
dc.contributor.authorMozafari, M.*
dc.contributor.authorYouseffi, Mansour*
dc.contributor.authorSefat, Farshid*
dc.date.accessioned2019-04-29T09:42:07Z
dc.date.available2019-04-29T09:42:07Z
dc.date.issued2017-09-26
dc.identifier.citationKaur P, Khaghani SA, Oluwadamilola A et al (2017) Fabrication and characterizations of hydrogels for cartilage repair. Tissue Engineering and Regenerative Medicine: Open Access. 2(6): 283-288.en_US
dc.identifier.urihttp://hdl.handle.net/10454/16991
dc.descriptionYesen_US
dc.description.abstractArticular cartilage is a vascular tissue with limited repair capabilities, leaving an afflicted person in extreme pain. The tissue experiences numerous forces throughout its lifetime. This study focuses on development of a novel hydrogel composed of chitosan and β-glycerophosphate for articular cartilage repair. The aim of this study was to investigate the mechanical properties and swelling behaviour of a novel hydrogel composed of chitosan and β-glycerophosphate for cartilage repair. The mechanical properties were measured for compression forces. Mach-1 mechanical testing system was used to obtain storage and loss modulus for each hydrogel sample to achieve viscoelastic properties of fabricated hydrogels. Two swelling tests were carried out to compare water retaining capabilities of the samples. The hydrogel samples were made of five different concentrations of β-glycerophosphate cross-linked with chitosan. Each sample with different β-glycerophosphate concentration underwent sinusoidal compression forces at three different frequencies -0.1Hz, 0.316Hz and 1Hz. The result of mechanical testing was obtained as storage and loss modulus. Storage modulus represents the elastic component and loss modulus represents the viscosity of the samples. The results obtained for 1Hz were of interest because the knee experiences frequency of 1Hz during walking.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttps://doi.org/10.15406/atroa.2017.02.00051en_US
dc.rights©2017 Kaur et al. This is an Open Access article distributed under the terms of the Creative Commons CC-BY-NC License , which permits unrestricted use, distribution, and build upon your work non-commercially (https://creativecommons.org/licenses/by-nc/4.0/)en_US
dc.subjectArticular cartilegeen_US
dc.subjectChitosanen_US
dc.subjectCross-linkeren_US
dc.subjectHydrogelen_US
dc.subjectLoss modulusen_US
dc.subjectScaffolden_US
dc.subjectStorage modulusen_US
dc.subjectSwelling propertyen_US
dc.subjectViscoelasticen_US
dc.titleFabrication and characterizations of hydrogels for cartilage repairen_US
dc.status.refereedYesen_US
dc.typeArticleen_US
dc.type.versionPublished versionen_US
refterms.dateFOA2019-04-29T09:42:07Z


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