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dc.contributor.authorJoshi, A.*
dc.contributor.authorGislason-Lee, Amber J.*
dc.contributor.authorSivananthan, U.M.*
dc.contributor.authorDavies, A.G.*
dc.date.accessioned2019-04-11T10:15:50Z
dc.date.available2019-04-11T10:15:50Z
dc.date.issued2017-03-03
dc.identifier.citationJoshi A, Gislason-Lee AJ, Sivananthan UM et al (2017) Can image enhancement allow radiation dose to be reduced whilst maintaining the perceived diagnostic image quality required for coronary angiography? British Journal of Radiology. 90(1071): 20160660en_US
dc.identifier.urihttp://hdl.handle.net/10454/16959
dc.descriptionYesen_US
dc.description.abstractDigital image processing used in modern cardiac interventional x-ray systems may have the potential to enhance image quality such that it allows for lower radiation doses. The aim of this research was to quantify the reduction in radiation dose facilitated by image processing alone for percutaneous coronary intervention (PCI) patient angiograms, without reducing the perceived image quality required to confidently make a diagnosis. Incremental amounts of image noise were added to five PCI patient angiograms, simulating the angiogram having been acquired at corresponding lower dose levels (by 10-89% dose reduction). Sixteen observers with relevant background and experience scored the image quality of these angiograms in three states - with no image processing and with two different modern image processing algorithms applied; these algorithms are used on state-of-the-art and previous generation cardiac interventional x-ray systems. Ordinal regression allowing for random effects and the delta method were used to quantify the dose reduction allowed for by the processing algorithms, for equivalent image quality scores. The dose reductions [with 95% confidence interval] from the state-of-the-art and previous generation image processing relative to no processing were 24.9% [18.8- 31.0%] and 15.6% [9.4-21.9%] respectively. The dose reduction enabled by the state-of-the-art image processing relative to previous generation processing was 10.3% [4.4-16.2%]. This demonstrates that statistically significant dose reduction can be facilitated with no loss in perceived image quality using modern image enhancement; the most recent processing algorithm was more effective in preserving image quality at lower doses.en_US
dc.description.sponsorshipThe study was funded by Philips Healthcare (the Netherlands).en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttps://doi.org/10.1259/bjr.20160660en_US
dc.rights© 2017 The Authors. Published by the British Institute of Radiology. Reproduced by permission from the copyright holder.en_US
dc.subjectCoronary angiography,en_US
dc.subjectDigital image enhancementen_US
dc.subjectImage qualityen_US
dc.subjectObserver studyen_US
dc.subjectRadiation dose reductionen_US
dc.subjectNoise simulationen_US
dc.titleCan image enhancement allow radiation dose to be reduced whilst maintaining the perceived diagnostic image quality required for coronary angiography?en_US
dc.status.refereedYesen_US
dc.date.Accepted2017-01-24
dc.date.application2017-03-03
dc.typeArticleen_US
dc.type.versionPublished versionen_US
refterms.dateFOA2019-04-11T10:15:50Z


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