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dc.contributor.authorSturm, G.J.
dc.contributor.authorVarga, E.M.
dc.contributor.authorRoberts, G.
dc.contributor.authorMosbech, H.
dc.contributor.authorBilo, M.B.
dc.contributor.authorAkdis, C.A.
dc.contributor.authorAntolın-Amerigo, D.
dc.contributor.authorCichocka-Jarosz, E.
dc.contributor.authorGawlik, R.
dc.contributor.authorJakob, T.
dc.contributor.authorKosnik, M.
dc.contributor.authorLange, J.
dc.contributor.authorMingomataj, E.
dc.contributor.authorMitsias, D.I.
dc.contributor.authorOllert, M.
dc.contributor.authorOude Elberink, J.N.G.
dc.contributor.authorPfaar, O.
dc.contributor.authorPitsios, C.
dc.contributor.authorPravettoni, V.
dc.contributor.authorRueff, F.
dc.contributor.authorSin, B.A.
dc.contributor.authorAgache, I.
dc.contributor.authorAngier, E.
dc.contributor.authorArasi, S.
dc.contributor.authorCalderon, M.A.
dc.contributor.authorFernandez-Rivas, M.
dc.contributor.authorHalken, S.
dc.contributor.authorJutel, M.
dc.contributor.authorLau, S.
dc.contributor.authorPajno, G.B.
dc.contributor.authorvan Ree, R.
dc.contributor.authorRyan, D.
dc.contributor.authorSpranger, O.
dc.contributor.authorvan Wijk, R.G.
dc.contributor.authorDhami, S.
dc.contributor.authorZaman, Hadar
dc.contributor.authorSheikh, A.
dc.contributor.authorMuraro, A.
dc.date.accessioned2018-07-10T11:50:25Z
dc.date.available2018-07-10T11:50:25Z
dc.date.issued2018-04-16
dc.identifier.citationSturm GJ, Varga EM, Roberts G et al (2018) EAACI guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy. 73(4): 744-764.en_US
dc.identifier.urihttp://hdl.handle.net/10454/16441
dc.descriptionYesen_US
dc.description.abstractHymenoptera venom allergy is a potentially life‐threatening allergic reaction following a honeybee, vespid, or ant sting. Systemic‐allergic sting reactions have been reported in up to 7.5% of adults and up to 3.4% of children. They can be mild and restricted to the skin or moderate to severe with a risk of life‐threatening anaphylaxis. Patients should carry an emergency kit containing an adrenaline autoinjector, H1‐antihistamines, and corticosteroids depending on the severity of their previous sting reaction(s). The only treatment to prevent further systemic sting reactions is venom immunotherapy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Taskforce on Venom Immunotherapy as part of the EAACI Guidelines on Allergen Immunotherapy initiative. The guideline aims to provide evidence‐based recommendations for the use of venom immunotherapy, has been informed by a formal systematic review and meta‐analysis and produced using the Appraisal of Guidelines for Research and Evaluation (AGREE II) approach. The process included representation from a range of stakeholders. Venom immunotherapy is indicated in venom‐allergic children and adults to prevent further moderate‐to‐severe systemic sting reactions. Venom immunotherapy is also recommended in adults with only generalized skin reactions as it results in significant improvements in quality of life compared to carrying an adrenaline autoinjector. This guideline aims to give practical advice on performing venom immunotherapy. Key sections cover general considerations before initiating venom immunotherapy, evidence‐based clinical recommendations, risk factors for adverse events and for relapse of systemic sting reaction, and a summary of gaps in the evidence.en_US
dc.description.sponsorshipEuropean Union's Seventh Framework Programme FP7. Grant Number: 601763en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttps://doi.org/10.1111/all.13262en_US
dc.subjectHymenoptera venom allergyen_US
dc.subjectAnaphylaxisen_US
dc.subjectVenom immunotherapyen_US
dc.subjectSafetyen_US
dc.subjectEffectivenessen_US
dc.titleEAACI guidelines on allergen immunotherapy: Hymenoptera venom allergyen_US
dc.status.refereedYesen_US
dc.date.Accepted2017-07-21
dc.date.application2017-12-05
dc.typeArticleen_US
dc.type.versionAccepted Manuscripten_US
refterms.dateFOA2018-12-10T10:08:00Z


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