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dc.contributor.authorNourrit, V.*
dc.contributor.authorDenniss, Jonathan*
dc.contributor.authorMugit, M.M.*
dc.contributor.authorSchiessl, I.*
dc.contributor.authorFenerty, C.*
dc.contributor.authorStanga, P.E.*
dc.contributor.authorHenson, D.B.*
dc.date.accessioned2018-06-26T08:15:07Z
dc.date.available2018-06-26T08:15:07Z
dc.identifier.citationNourrit V, Denniss J, Mugit MM et al (2010) High-resolution hyperspectral imaging of the retina with a modified fundus camera. Journal Francais D'Ophtalmologie. 33(10): 686-692.en_US
dc.identifier.urihttp://hdl.handle.net/10454/16323
dc.descriptionNoen_US
dc.description.abstractThe purpose of the research was to examine the practical feasibility of developing a hyperspectral camera from a Zeiss fundus camera and to illustrate its use in imaging diabetic retinopathy and glaucoma patients. The original light source of the camera was replaced with an external lamp filtered by a fast tunable liquid-crystal filter. The filtered light was then brought into the camera through an optical fiber. The original film camera was replaced by a digital camera. Images were obtained in normals and patients (primary open angle glaucoma, diabetic retinopathy) recruited at the Manchester Royal Eye Hospital. A series of eight images were captured across 495- to 720-nm wavelengths, and recording time was less than 1.6s. The light level at the cornea was below the ANSI limits, and patients judged the measurement to be very comfortable. Images were of high quality and were used to generate a pixel-to-pixel oxygenation map of the optic nerve head. Frame alignment is necessary for frame-to-frame comparison but can be achieved through simple methods. We have developed a hyperspectral camera with high spatial and spectral resolution across the whole visible spectrum that can be adapted from a standard fundus camera. The hyperspectral technique allows wavelength-specific visualization of retinal lesions that may be subvisible using a white light source camera. This hyperspectral technique may facilitate localization of retinal and disc pathology and consequently facilitate the diagnosis and management of retinal disease.en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttps://doi.org/10.1016/j.jfo.2010.10.010en_US
dc.subjectRetinaen_US
dc.subjectHigh-resolution hyperspectral imagingen_US
dc.subjectFundus cameraen_US
dc.titleHigh-resolution hyperspectral imaging of the retina with a modified fundus cameraen_US
dc.status.refereedYesen_US
dc.typeArticleen_US
dc.type.versionNo full-text in the repositoryen_US


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