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    Nanoparticles in Biomedicine and Medicine, and Possible Clinical Toxicological Application of Peripheral Lymphocytes in the Risk Assessment Process for Susceptible Disease State Individuals

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    Publication date
    2017-11-13
    Author
    Najafzadeh, Mojgan
    Anderson, Diana
    Keyword
    Nanoparticles
    Peripheral lymphocytes
    Risk assessment
    Medicine
    Biomedicine
    Peer-Reviewed
    No
    
    Metadata
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    Abstract
    Nanoparticle usage has emerged in the medical field as a technology well-suited to the diagnosis and treatment of a variety of disease states. The distinctive characteristics of engineered nanoparticles (ENPs) such as higher surface-area-to-volume ratios find various applications in personal care products, food packaging, drug-delivery systems, therapeutics, biosensors and others. The exponential increase in ENP-containing consumer products in the last decade has also increased their inadvertent release into the environment and the debate relating to their adverse effects on human and environmental health. The use of NPs for different functions in human studies has significantly increased the application of NPs in biomedicine, for instance, imaging of cell and tissues, drug delivery and sensing of target molecules. These nanomaterials have been investigated for the treatment and detection of various pathological conditions. There are suitable biological systems now available in man using peripheral blood lymphocytes to determine the effect of NPs in various disease states.
    URI
    http://hdl.handle.net/10454/15721
    Version
    No full-text in the repository
    Citation
    Najafzadeh M and Anderson D (2017) Nanoparticles in Biomedicine and Medicine, and Possible Clinical Toxicological Application of Peripheral Lymphocytes in the Risk Assessment Process for Susceptible Disease State Individuals. In: Dhawan A, Anderson D and Shanker R (Eds) Nanotoxicology: Experimental and Computational Perspectives. Cambridge, UK: Royal Society of Chemistry.
    Link to publisher’s version
    http://pubs.rsc.org/en/content/chapter/bk9781782621584-00133/978-1-78262-392-2
    Type
    Book chapter
    Collections
    Life Sciences Publications

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