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dc.contributor.authorSun, L.
dc.contributor.authorPitto-Barry, Anaïs
dc.contributor.authorThomas, A.W.
dc.contributor.authorInam, M.
dc.contributor.authorDoncom, K.E.B.
dc.contributor.authorDove, A.P.
dc.contributor.authorO'Reilly, R.K.
dc.date.accessioned2018-03-29T14:38:13Z
dc.date.available2018-03-29T14:38:13Z
dc.date.issued2016-04-07
dc.identifier.citationSun L, Pitto-Barry A, Thomas AW, Inam M, Dove AP and O'Reilly RK (2016) Core functionalization of semi-crystalline polymeric cylindrical nanoparticles using photo-initiated thiol–ene radical reactions. Polymer Chemistry. 7(13): 2337-2341.en_US
dc.identifier.urihttp://hdl.handle.net/10454/15390
dc.descriptionyesen_US
dc.description.abstractSequential ring-opening and reversible addition–fragmentation chain transfer (RAFT) polymerization was used to form a triblock copolymer of tetrahydropyran acrylate (THPA), 5-methyl-5-allyloxycarbonyl-1,3-dioxan-2-one (MAC) and L-lactide. Concurrent deprotection of the THPA block and crystallization-driven self-assembly (CDSA) was undertaken and allowed for the formation of cylindrical micelles bearing allyl handles in a short outer core segment. These handles were further functionalized by different thiols using photo-initiated thiol–ene radical reactions to demonstrate that the incorporation of an amorphous PMAC block within the core does not disrupt CDSA and can be used to load the cylindrical nanoparticles with cargo.en_US
dc.description.sponsorshipRoyal Society (Great Britain), Engineering and Physical Sciences Research Council (EPSRC), European Research Council (ERC)en_US
dc.language.isoenen_US
dc.relation.isreferencedbyhttp://dx.doi.org/10.1039/C5PY01970Ben_US
dc.rights© 2016 RSC. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.en_US
dc.subjectCrystallisation-driven self-assembly; Post-assembly modification: Post-polymerisation modification; Polylactide; Cylindrical micellesen_US
dc.titleCore functionalization of semi-crystalline polymeric cylindrical nanoparticles using photo-initiated thiol–ene radical reactionsen_US
dc.status.refereedYesen_US
dc.date.Accepted2016-02-12
dc.date.application2016-02-25
dc.typeArticleen_US
dc.type.versionPublished versionen_US


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