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dc.contributor.authorSanni, O.*
dc.contributor.authorChang, Chien-Yi*
dc.contributor.authorAnderson, D.G.*
dc.contributor.authorLanger, R.*
dc.contributor.authorDavies, M.C.*
dc.contributor.authorWilliams, P.M.*
dc.contributor.authorWilliams, P.*
dc.contributor.authorAlexander, M.R.*
dc.contributor.authorHook, A.L.*
dc.date.accessioned2018-02-23T16:58:44Z
dc.date.available2018-02-23T16:58:44Z
dc.date.issued2015-04-02
dc.identifier.citationSanni O, Chang C, Anderson DG et al (2015) Bacterial attachment to polymeric materials correlates with molecular flexibility and hydrophilicity. Advanced Healthcare Materials. 4(5): 695- 701.
dc.identifier.urihttp://hdl.handle.net/10454/15067
dc.descriptionYes
dc.description.abstractA new class of material resistant to bacterial attachment has been discovered that is formed from polyacrylates with hydrocarbon pendant groups. In this study, the relationship between the nature of the hydrocarbon moiety and resistance to bacteria is explored, comparing cyclic, aromatic, and linear chemical groups. A correlation is shown between bacterial attachment and a parameter derived from the partition coefficient and the number of rotatable bonds of the materials' pendant groups. This correlation is applicable to 86% of the hydrocarbon pendant moieties surveyed, quantitatively supporting the previous qualitative observation that bacteria are repelled from poly(meth)acrylates containing a hydrophilic ester group when the pendant group is both rigid and hydrophobic. This insight will help inform and predict the further development of polymers resistant to bacterial attachment.
dc.description.sponsorshipWellcome Trust (grant number 085245) and EMRP (IND56)
dc.language.isoen
dc.rights© 2014 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.subjectLow-fouling
dc.subjectMolecular descriptors
dc.subjectPolymer microarrays
dc.subjectPseudomonas aeruginosa
dc.subjectIon mass spectrometry
dc.titleBacterial attachment to polymeric materials correlates with molecular flexibility and hydrophilicity
dc.status.refereedYes
dc.date.Accepted2014
dc.date.application2014-12-09
dc.typeArticle
dc.type.versionPublished version
dc.identifier.doihttps://doi.org/10.1002/adhm.201400648
dc.rights.licenseCC-BY
refterms.dateFOA2018-07-28T03:15:57Z
dc.openaccess.statusopenAccess


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