Does transient increase in axial length elongation during accommodation attenuate with age?
|dc.contributor.author||Mallen, Edward A.H.||*|
|dc.identifier.citation||Laughton DS, Sheppard AL, Mallen EAH et al (2017) Does transient increase in axial length during accommodation attenuate with age? Clinical and Experimental Optometry. 100(6): 676-682.||en_US|
|dc.description.abstract||Background: The aim was to profile transient accommodative axial length changes from early adulthood to advanced presbyopia and to determine whether any differences exist between the responses of myopic and emmetropic individuals. Methods: Ocular biometry was measured by the LenStar biometer (Haag-Streit, Switzerland) in response to zero, 3.00 and 4.50 D accommodative stimuli in 35 emmetropes and 37 myopes, aged 18 to 60 years. All results were corrected to reduce errors arising from the increase in crystalline lens thickness with accommodation. Accommodative responses were measured sequentially by the WAM 5500 Auto Ref/Keratometer (Grand Seiko, Hiroshima, Japan). Results: Axial length increased significantly with accommodation (p < 0.001), with a mean corrected increase in axial length of 2 18 μm and 8 16 μm observed at 3.00 and 4.50 D, respectively. The magnitude of accommodative change in axial length was not dependent on refractive error classification (p = 0.959); however, a significant reduction in the magnitude and variance of axial length change was evident after 43 to 44 years of age (p < 0.002). Conclusion: The negative association between transient increase in axial length and age, in combination with reduced variance of data after age 43 to 44 years, is consistent with a significant increase in posterior ocular rigidity, which may be influential in the development of presbyopia.||en_US|
|dc.description.sponsorship||DL received funds from the College of Optometrists, UK||en_US|
|dc.rights||© 2017 The Authors. Clinical and Experimental Optometry published by John Wiley & Sons Australia, Ltd on behalf of Optometry Australia. This is an open access article under the terms of the Creative Commons Attribution- NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.||en_US|
|dc.subject||Accommodation; Axial length; Biometry; Crystalline lens; Presbyopia||en_US|
|dc.title||Does transient increase in axial length elongation during accommodation attenuate with age?||en_US|